Pressure effects on lipid membrane structure and dynamics

被引:53
作者
Brooks, Nicholas J. [1 ]
Ces, Oscar [1 ]
Templer, Richard H. [1 ]
Seddon, John M. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, Inst Biol Chem, London SW7 2AZ, England
基金
英国工程与自然科学研究理事会;
关键词
High pressure; Lipids; Structure; SAXS; Phase behaviour; X-RAY-DIFFRACTION; BICONTINUOUS CUBIC PHASES; HIGH HYDROSTATIC-PRESSURE; NUCLEAR-MAGNETIC-RESONANCE; JUMP RELAXATION TECHNIQUE; DIAMOND-ANVIL TECHNIQUE; SMALL-ANGLE; INFRARED-SPECTROSCOPY; FTIR SPECTROSCOPY; FLUID MEMBRANES;
D O I
10.1016/j.chemphyslip.2010.12.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The effect of hydrostatic pressure on lipid structure and dynamics is highly important as a tool in biophysics and bio-technology, and in the biology of deep sea organisms. Despite its importance, high hydrostatic pressure remains significantly less utilised than other thermodynamic variables such as temperature and chemical composition. Here, we give an overview of some of the theoretical aspects which determine lipid behaviour under pressure and the techniques and technology available to study these effects. We also summarise several recent experiments which highlight the information available from these approaches. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:89 / 98
页数:10
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