A calibration strategy for LA-ICP-MS using isotope dilution for solid reference materials

被引：15
作者：
Thieleke, J. P. [1 ]
Vogt, C. [1 ]
机构：
[1] Leibniz Univ Hannover, Inst Inorgan Chem, Callinstr 9, D-30167 Hannover, Germany
来源：
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY | 2016年 / 31卷 / 06期
关键词：
PLASMA-MASS SPECTROMETRY; LASER-ABLATION; THIN-SECTIONS; HUMAN BRAIN; COPPER; ZINC; LOCALIZATION; PLATINUM; NANOSIMS; ELEMENTS;
D O I：
10.1039/c6ja00042h
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
An isotope dilution method for the quantitative analysis of trace elements in biological samples and for the characterization of reference materials for the analysis of biological samples by laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-ID-MS) has been tested. Polymeric thin layers with 5-10 mu m thickness containing the ID-spike and the correction standard were produced by knife application onto polyester substrates. For the ID experiments (204Pb) enriched lead was used, and bismuth served as the internal standard. The layers showed good homogeneity of the layer thickness and the distribution of added elements. For the testing of the ID method, a synthetic sample with lead and a lead containing polymer certified reference material (BAM H010) have been used. Mass fractions for lead calculated after single and double isotope dilution experiments in the test samples showed a deviation of less than 1% from the certified values.
引用
收藏
页码：1198 / 1205
页数：8
相关论文
共 37 条
[1]   Quantification method for elemental bio-imaging by LA-ICP-MS using metal spiked PMMA films [J].
Austin, Christine ;
Hare, Dominic ;
Rawling, Tristan ;
McDonagh, Andrew M. ;
Doble, Philip .
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY, 2010, 25 (05) :722-725
[2]  
BAM Federal Institute for Materials Research and Testing, 2013, CERT REF MAT BAM H01
[3]   Quantitative imaging of selenium, copper, and zinc in thin sections of biological tissues (Slugs-Genus arion) measured by laser ablation inductively coupled of plasma mass spectrometry [J].
Becker, J. S. ;
Matusch, A. ;
Depboylu, C. ;
Dobrowolska, J. ;
Zoriy, M. V. .
ANALYTICAL CHEMISTRY, 2007, 79 (16) :6074-6080
[4]   Quantitative images of metals in plant tissues measured by laser ablation inductively coupled plasma mass spectrometry [J].
Becker, J. S. ;
Dietrich, R. C. ;
Matusch, A. ;
Pozebon, D. ;
Dressier, V. L. .
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY, 2008, 63 (11) :1248-1252
[5]   Bioimaging mass spectrometry of trace elements - recent advance and applications of LA-ICP-MS: A review [J].
Becker, J. Sabine ;
Matusch, Andreas ;
Wu, Bei .
ANALYTICA CHIMICA ACTA, 2014, 835 :1-18
[6]   Bioimaging of metals in brain tissue from micrometre to nanometre scale by laser ablation inductively coupled plasma mass spectrometry: State of the art and perspectives [J].
Becker, J. Sabine .
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2010, 289 (2-3) :65-75
[7]   Imaging of copper, zinc, and other elements in thin section of human brain samples (Hippocampus) by laser ablation inductively coupled plasma mass spectrometry [J].
Becker, JS ;
Zoriy, MV ;
Pickhardt, C ;
Palomero-Gallagher, N ;
Zilles, K .
ANALYTICAL CHEMISTRY, 2005, 77 (10) :3208-3216
[8]   Copper, zinc, phosphorus and sulfur distribution in thin section of rat brain tissues measured by laser ablation inductively coupled plasma mass spectrometry: possibility for small-size tumor analysis [J].
Becker, JS ;
Zoriy, MV ;
Pickhardta, C ;
Zilles, K .
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY, 2005, 20 (09) :912-917
[9]   Determination of Ag, Tl, and Pb in few milligrams of platinum nanoclusters by on-line isotope dilution in laser ablation inductively coupled plasma mass spectrometry [J].
Becker, JS ;
Pickhardt, C ;
Pompe, W .
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 2004, 237 (01) :13-17
[10]   Laser ablation for analytical sampling: what can we learn from modeling? [J].
Bogaerts, A ;
Chen, ZY ;
Gijbels, R ;
Vertes, A .
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY, 2003, 58 (11) :1867-1893
1234