Evaluation of an oral appliance in patients with mild to moderate obstructive sleep apnea syndrome intolerant to continuous positive airway pressure use: Preliminary results

被引:35
作者
Cantore, S. [1 ]
Ballini, A. [1 ]
Farronato, D. [2 ]
Malcangi, G. [3 ]
Dipalma, G. [3 ]
Assandri, F. [4 ]
Garagiola, U. [4 ]
Inchingolo, F. [3 ]
De Vito, D. [1 ]
Cirulli, N. [1 ]
机构
[1] Univ Bari Aldo Moro, Dept Basic Med Sci Neurosci & Sense Organs, Pzza Giulio Cesare 11, I-70124 Bari, Italy
[2] Insubria Univ, Dept Morphol & Surg Sci, Varese, Italy
[3] Univ Bari Aldo Moro, Dept Interdisciplinary Med, Bari, Italy
[4] Univ Milan, Dept Biomed Surg & Dent Sci, Unit Orthodont & Paediat Dent, Milan, Italy
关键词
apnea-hypopnea index; continuous positive airway pressure; obstructive sleep apnea syndrome; oral appliance; Thornton Adjustable Positioner; MANAGEMENT; THERAPY;
D O I
10.1177/0394632015590949
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Obstructive sleep apnea syndrome (OSAS) is a phenomenon of repeated, episodic reduction, or cessation of airflow (hypopnea/apnea) as a result of upper airways obstruction. First-line treatment in younger children is adenotonsillectomy, although other available treatment options in middle-aged adults include continuous positive airways pressure (CPAP) and airway adjuncts. Oral appliances (OA) are a viable treatment alternative in patients with OSAS. The objective of this study was to assess, in a 1-year follow-up study, an OA in OSAS patients. The participants were subjected to polysomnographic examination with a validated device (MicroMESAM). Eight participants were fitted with a Thornton Adjustable Positioner (TAP). The participants were asked to wear the test appliance for 7 nights, and in case of compliance, for 6 months. The selected patients record their usage of the appliance and any adverse effects in a treatment journal. The research focused on the following outcomes: sleep apnea (i.e. reduction in the apnea/hypopnea index) and the effect of oral appliances on daytime function. In conclusion, the results suggest that OA have a definite role in the treatment of snoring and sleep apnea.
引用
收藏
页码:267 / 273
页数:7
相关论文
共 27 条
[1]  
[Anonymous], 2012, AASM MAN SCOR SLEEP
[2]   Effectiveness of Lifestyle Interventions on Obstructive Sleep Apnea (OSA): Systematic Review and Meta-Analysis [J].
Araghi, Marzieh Hosseini ;
Chen, Yen-Fu ;
Jagielski, Alison ;
Choudhury, Sopna ;
Banerjee, Dev ;
Hussain, Shakir ;
Thomas, G. Neil ;
Taheri, Shahrad .
SLEEP, 2013, 36 (10) :1553-1562
[3]   Practice Parameters for the Surgical Modifications of the Upper Airway for Obstructive Sleep Apnea in Adults [J].
Aurora, R. Nisha ;
Casey, Kenneth R. ;
Kristo, David ;
Auerbach, Sanford ;
Bista, Sabin R. ;
Chowdhuri, Susmita ;
Karippot, Anoop ;
Lamm, Carin ;
Ramar, Kannan ;
Zak, Rochelle ;
Morgenthaler, Timothy I. .
SLEEP, 2010, 33 (10) :1408-1413
[4]   Oral Appliance Versus Continuous Positive Airway Pressure in Obstructive Sleep Apnea Syndrome: A 2-Year Follow-up [J].
Doff, Michiel H. J. ;
Hoekema, Aarnoud ;
Wijkstra, Peter J. ;
van der Hoeven, Johannes H. ;
Slater, James J. R. Huddleston ;
de Bont, Lambert G. M. ;
Stegenga, Boudewijn .
SLEEP, 2013, 36 (09) :1289-1296
[5]   Oral appliances for snoring and obstructive sleep apnea: A review [J].
Ferguson, Kathleen A. ;
Cartwright, Rosalind ;
Rogers, Robert ;
Schmidt-Nowara, Wolfgang .
SLEEP, 2006, 29 (02) :244-262
[6]  
Freedman Neil, 2014, F1000Prime Rep, V6, P36, DOI 10.12703/P6-36
[7]   Do oral appliances enlarge the airway in patients with obstructive sleep apnoea? A prospective computerized tomographic study [J].
Gale, DJ ;
Sawyer, RH ;
Woodcock, A ;
Stone, P ;
Thompson, R ;
O'Brien, K .
EUROPEAN JOURNAL OF ORTHODONTICS, 2000, 22 (02) :159-168
[8]   A randomized prospective long-term study of two oral appliances for sleep apnoea treatment [J].
Ghazal, Akssam ;
Sorichter, Stefan ;
Jonas, Irmtrud ;
Rose, Edmund C. .
JOURNAL OF SLEEP RESEARCH, 2009, 18 (03) :321-328
[9]   Continuous positive airways pressure for obstructive sleep apnoea in adults [J].
Giles, TL ;
Lasserson, TJ ;
Smith, BJ ;
White, J ;
Wright, J ;
Cates, CJ .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2006, (01)
[10]  
HANDELMAN CS, 1976, ANGLE ORTHOD, V46, P243