Outcomes after central grey matter injury in term perinatal hypoxic-ischaemic encephalopathy

被引：95

作者：

Martinez-Biarge, Miriam ^{[1
,2
]}

Diez-Sebastian, Jesus ^{[3
]}

Rutherford, Mary A. ^{[4
]}

Cowan, Frances M. ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Paediat & Imaging Sci, London, England

[2] La Paz Univ Hosp, Dept Neonatol, Madrid, Spain

[3] La Paz Univ Hospital, Dept Biostat, Madrid, Spain

[4] Univ London Imperial Coll Sci Technol & Med, MRC Clin Sci Ctr, Imaging Sci Dept, Robert Steiner MR Unit, London, England

来源：

EARLY HUMAN DEVELOPMENT | 2010年 / 86卷 / 11期

基金：

英国医学研究理事会;

关键词：

Perinatal; Basal ganglia; Thalami; MRI; Outcome; Term; GROSS MOTOR FUNCTION; CEREBRAL-PALSY; VISUAL FUNCTION; BASAL GANGLIA; CHILDREN; IMPAIRMENT; PREVALENCE; SEVERITY; INFANTS; SCORE;

D O I：

10.1016/j.earlhumdev.2010.08.013

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Central grey matter damage following perinatal hypoxia-ischaemia frequently leads to death or motor abnormality often with deficits in other developmental domains. Predicting these different outcomes is difficult yet very important for early management, planning and providing for needs on discharge and later and not least for parents to know how their children will be affected. The best single predictor of the pattern of outcomes for an individual infant is an early MRI scan. We present a guide for predicting outcome at 2 years in different developmental domains based on the severity of injury seen in the basal ganglia and thalami (BGT) on neonatal MRI. (C) 2010 Elsevier Ireland Ltd. All rights reserved.

引用

页码：675 / 682

页数：8

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