Anandamide serves two masters in the brain

被引：29

作者：

Di Marzo, Vincenzo ^{[1
]}

机构：

[1] CNR, Endocannabinoid Res Grp, Inst Biomol Chem, Pozzuoli, NA, Italy

来源：

NATURE NEUROSCIENCE | 2010年 / 13卷 / 12期

关键词：

CENTRAL-NERVOUS-SYSTEM; RECEPTOR; TRPV1; CHANNELS; TYPE-1; MICE; MEDIATE;

D O I：

10.1038/nn1210-1446

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Two studies in this issue find that postsynaptic TRPV1 receptors affect AMPA receptor endocytosis to mediate anandamide-induced long-term depression in the hippocampus and nucleus accumbens. © 2010 Nature America, Inc. All rights reserved.

引用

页码：1446 / 1448

页数：4

共 15 条

[1] Deletion of vanilloid receptor (TRPV1) in mice alters behavioral effects of ethanol [J].

Blednov, Y. A. ;

Harris, R. A. .

NEUROPHARMACOLOGY, 2009, 56 (04) :814-820

[2] TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus [J].

Chavez, Andres E. ;

Chiu, Chiayu Q. ;

Castillo, Pablo E. .

NATURE NEUROSCIENCE, 2010, 13 (12) :1511-U99

[3] Immunohistochemical localization of cannabinoid type 1 and vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain [J].

Cristino, L. ;

De Petrocellis, L. ;

Pryce, G. ;

Baker, D. ;

Guglielmotti, V. ;

Di Marzo, V. .

NEUROSCIENCE, 2006, 139 (04) :1405-1415

[4] Involvement of vanilloid-like receptors in the effects of anandamide on motor behavior and nigrostriatal dopaminergic activity:: in vivo and in vitro evidence [J].

de Lago, E ;

de Miguel, R ;

Lastres-Becker, I ;

Ramos, JA ;

Fernández-Ruiz, J .

BRAIN RESEARCH, 2004, 1007 (1-2) :152-159

[5] ISOLATION AND STRUCTURE OF A BRAIN CONSTITUENT THAT BINDS TO THE CANNABINOID RECEPTOR [J].

DEVANE, WA ;

HANUS, L ;

BREUER, A ;

PERTWEE, RG ;

STEVENSON, LA ;

GRIFFIN, G ;

GIBSON, D ;

MANDELBAUM, A ;

ETINGER, A ;

MECHOULAM, R .

SCIENCE, 1992, 258 (5090) :1946-1949

[6] TRPV1 channels mediate long-term depression at synapses on hippocampal interneurons [J].

Gibson, Helen E. ;

Edwards, Jeffrey G. ;

Page, Rachel S. ;

Van Hook, Matthew J. ;

Kauer, Julie A. .

NEURON, 2008, 57 (05) :746-759

[7] Postsynaptic TRPV1 triggers cell type-specific long-term depression in the nucleus accumbens [J].

Grueter, Brad A. ;

Brasnjo, Gabor ;

Malenka, Robert C. .

NATURE NEUROSCIENCE, 2010, 13 (12) :1519-U107

[8] Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum [J].

Maccarrone, Mauro ;

Rossi, Silvia ;

Bari, Monica ;

De Chiara, Valentina ;

Fezza, Filomena ;

Musella, Alessandra ;

Gasperi, Valeria ;

Prosperetti, Chiara ;

Bernardi, Giorgio ;

Finazzi-Agro, Alessandro ;

Cravatt, Benjamin F. ;

Centonze, Diego .

NATURE NEUROSCIENCE, 2008, 11 (02) :152-159

[9] TRPV1 channels control synaptic plasticity in the developing superior colliculus [J].

Maione, Sabatino ;

Cristino, Luigia ;

Migliozzi, Anna Lucia ;

Georgiou, Anne L. ;

Starowicz, Katarzyna ;

Salt, Thomas E. ;

Di Marzo, Vincenzo .

JOURNAL OF PHYSIOLOGY-LONDON, 2009, 587 (11) :2521-2535

[10] Reduced anxiety, conditioned fear, and hippocampal long-term Potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice [J].

Marsch, Rudolph ;

Foeller, Elisabeth ;

Rammes, Gerhard ;

Bunck, Mirjam ;

Koessl, Manfred ;

Holsboer, Florian ;

Zieglgaensberger, Walter ;

Landgraf, Rainer ;

Lutz, Beat ;

Wotjak, Carsten T. .

JOURNAL OF NEUROSCIENCE, 2007, 27 (04) :832-839

← 1 2 →