Traditional antimalarial phytotherapy remedies used by the South Coast community, Kenya

被引:33
作者
Nguta, J. M. [1 ]
Mbaria, J. M. [1 ]
Gakuya, D. W. [2 ]
Gathumbi, P. K. [3 ]
Kiama, S. G. [4 ]
机构
[1] Univ Nairobi, Dept Publ Hlth Pharmacol & Toxicol, Nairobi 00100, Kenya
[2] Univ Nairobi, Dept Clin Studies, Nairobi 00100, Kenya
[3] Univ Nairobi, Dept Vet Pathol Microbiol & Parasitol, Nairobi 00100, Kenya
[4] Univ Nairobi, Dept Vet Anat & Physiol, Nairobi 00100, Kenya
关键词
Traditional remedies; Antimalarial plants; Ethnopharmacology; South-Coast community; VITRO ANTIPLASMODIAL ACTIVITY; AFRICAN MEDICINAL-PLANTS; IN-VITRO; MALARIA; TANZANIA; HEALERS; PERCEPTION; INVENTORY; EXTRACTS; CHILDREN;
D O I
10.1016/j.jep.2010.06.031
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Aim of the study: This study was conducted to document herbal medicines used in the treatment of malaria as well as the existing knowledge, attitudes and practices related to malaria recognition, control and treatment in South Coast, Kenya. Methods. Data was collected using semistructured questionnaires and interviews A focused group discussion held with the community members, one in each of the study villages supplemented the interview and questionnaire survey Results: The respondents were found to have a good understanding of malaria and could distinguish it from other fever types. They were also aware that malaria was spread by mosquitoes. Malaria prevalence was high, and affected individuals an average of four times a year Community members avoided mosquito bites by using mosquito nets, clearing bushes around their homesteads and burning plant parts to generate smoke. They prevented and treated malaria by taking decoctions or concoctions of traditional herbal remedies. Forty plant species in thirty-five genera distributed in twenty-four families were used as antimalarials in the study area. Five plant species, namely; Heeria insignis Del. (Anacardiaceae), Rottboelia exaltata LF (Gramineae), Pentanisia ouranogyne S. Moore (Rubiaceae), Agathisanthenum globosum (A Rich) Hiern (Rubiaceae), and Grewia trichocarpa Hochst ex A. Rich (Tiliaceae) are documented for the first time in South Coast, Kenya, for the treatment of malaria Conclusions The plants documented in the current study are a potential source for new bioactive compounds of therapeutic value in malaria treatment. The results provide data for further pharmacological and toxicological studies and development of commercial antimalarial phytotherapy products (C) 2010 Elsevier Ireland Ltd All rights reserved.
引用
收藏
页码:256 / 267
页数:12
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