Inflammatory myofibroblastic tumour of the tonsil: case report and literature review

被引:3
作者
Magill, J. C. [1 ]
Ferguson, M. S. [1 ]
Butler, C. R. [1 ]
Sandison, A. [2 ]
Grant, W. E. [1 ]
机构
[1] Charing Cross Hosp, Dept Otolaryngol Head & Neck Surg, London W6 8RF, England
[2] Charing Cross Hosp, Dept Histopathol, London W6 8RF, England
关键词
Tonsil Neoplasms; Inflammatory Myofibroblastic Tumour; INDOLEAMINE 2,3-DIOXYGENASE; PSEUDOTUMOR; TOLERANCE; EXPRESSION;
D O I
10.1017/S0022215110000058
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objective: We present the first reported case in the English language literature of an inflammatory myofibroblastic tumour of the right tonsil in a young, pregnant woman. and we report a management strategy for this enigmatic entity Case report: A 28-year-old. pregnant woman presented with a 10-day history of odynophagia despite a course of antibiotics Examination revealed a grade II. erythematous tight tonsil with ulceration on the upper pole. A biopsy was arranged, and initial evaluation was suggestive of spindle cell carcinoma However. this diagnosis was reviewed after immunohistochemical staining confirmed an inflammatory myofibroblastic tumour Subsequent complete excision was undertaken using CO, laser. Conclusion Clinically: inflammatory myofibroblastic tumour of the tonsil is known to be locally aggressive and can present in a manner not dissimilar to a high glade carcinoma of the tonsil As a result, the recommended treatment is complete local excision with careful follow up.
引用
收藏
页码:1123 / 1125
页数:3
相关论文
共 14 条
[1]   The potential role of HLA-G polymorphism in maternal tolerance to the developing fetus [J].
Agrawal, S ;
Pandey, MK .
JOURNAL OF HEMATOTHERAPY & STEM CELL RESEARCH, 2003, 12 (06) :749-756
[2]   PATHOLOGY CONSULTATION - PLASMA-CELL TUMORS OF THE HEAD AND NECK [J].
BATSAKIS, JG .
ANNALS OF OTOLOGY RHINOLOGY AND LARYNGOLOGY, 1983, 92 (03) :311-313
[3]  
Coffin C. M., 2002, World Health Organization classification of tumours: Tumours of soft tissue and bone, P91
[4]   ALK1 and p80 expression and chromosomal rearrangements involving 2p23 in inflammatory myofibroblastic tumor [J].
Coffin, CM ;
Patel, A ;
Perkins, S ;
Elenitoba-Johnson, KSJ ;
Perlman, E ;
Griffin, CA .
MODERN PATHOLOGY, 2001, 14 (06) :569-576
[5]   EXTRAPULMONARY INFLAMMATORY MYOFIBROBLASTIC TUMOR (INFLAMMATORY PSEUDOTUMOR) - A CLINICOPATHOLOGICAL AND IMMUNOHISTOCHEMICAL STUDY OF 84 CASES [J].
COFFIN, CM ;
WATTERSON, J ;
PRIEST, JR ;
DEHNER, LP .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1995, 19 (08) :859-872
[6]   Inflammatory myofibroblastic tumour of the tonsil [J].
Gangopadhay, K ;
Mahasin, ZZ ;
Kfoury, H ;
Ali, MA .
JOURNAL OF LARYNGOLOGY AND OTOLOGY, 1997, 111 (09) :880-882
[7]   Indoleamine 2,3-dioxygenase (IDO) expression in invasive extravillous trophoblast supports role of the enzyme for materno-fetal tolerance [J].
Honig, A ;
Rieger, L ;
Kapp, M ;
Sütterlin, M ;
Dietl, J ;
Kämmerer, U .
JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2004, 61 (02) :79-86
[8]   Indoleamine 2,3-dioxygenase: distribution and function in the developing human placenta [J].
Kudo, Y ;
Boyd, CAR ;
Spyropoulou, I ;
Redman, CWG ;
Takikawa, O ;
Katsuki, T ;
Hara, T ;
Ohama, K ;
Sargent, IL .
JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2004, 61 (02) :87-98
[9]   The placental immunomodulatory cytokine regeneration and tolerance factor is also expressed by both human cycling and early pregnant endometrium [J].
Lattuada, D ;
Mangioni, S ;
Viganò, P ;
Ntrivalas, EI ;
Rossi, M ;
Palotti, F ;
Carinelli, S ;
Beaman, KD ;
Di Blasio, AM .
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2004, 52 (03) :224-231
[10]   INFLAMMATORY FIBROSARCOMA OF THE MESENTERY AND RETROPERITONEUM - A TUMOR CLOSELY SIMULATING INFLAMMATORY PSEUDOTUMOR [J].
MEIS, JM ;
ENZINGER, FM .
AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1991, 15 (12) :1146-1156