Nitric oxide detection methods in vitro and in vivo

被引：79

作者：

Goshi, Ekta ^{[1
]}

Zhou, Gaoxin ^{[1
]}

He, Qianjun ^{[1
,2
]}

机构：

[1] Shenzhen Univ, Guangdong Prov Key Lab Biomed Measurements & Ultr, Natl Reg Key Technol Engn Lab Med Ultrasound, Sch Biomed Engn,Hlth Sci Ctr, Shenzhen, Guangdong, Peoples R China

[2] Shanghai Jiao Tong Univ, Ctr Hydrogen Sci, Shanghai, Peoples R China

来源：

MEDICAL GAS RESEARCH | 2019年 / 9卷 / 04期

基金：

中国国家自然科学基金;

关键词：

nitric oxide; detection method; nitric oxide synthase; nitric oxide therapy; colorimetric; chemiluminescence; fluorescence; electrochemical; gas chromatography; magnetic resonance imaging; NITROSYL-IRON COMPLEXES; FLUORESCENT-PROBE; REAL-TIME; ELECTROCHEMICAL DETECTION; GRIESS REACTION; ENDOTHELIAL-CELLS; RELEASE; NO; SYNTHASE; NITRATE;

D O I：

10.4103/2045-9912.273957

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Initially being considered as an environmental pollutant, nitric oxide has gained the momentum of research since its discovery as endothelial derived growth factor in 1987. Extensive researches have revealed the various pathological and physiological roles of nitric oxide such as inflammation, vascular and neurological regulation functions. Hence, the development of methods for quantifying nitric oxide concentration and its metabolites will be beneficial to well know about its biological functions and effects. This review summaries various methods for in vitro and in vivo nitric oxide detection, and introduces their merits and demerits.

引用

页码：192 / 207

页数：16

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