Evidence-based guidelines for the pharmacological treatment of postmenopausal osteoporosis: a consensus document by the Belgian Bone Club

被引:87
作者
Body, J. -J. [2 ]
Bergmann, P. [3 ]
Boonen, S. [4 ]
Boutsen, Y. [5 ]
Devogelaer, J. -P. [6 ]
Goemaere, S. [7 ]
Kaufman, J. -M. [8 ]
Rozenberg, S. [9 ]
Reginster, J. -Y. [1 ,10 ]
机构
[1] CHU Ctr Ville, Bone & Cartilage Metab Res Unit, Policlin L BRULL, B-4020 Liege, Belgium
[2] Univ Libre Bruxelles, Dept Med, CHU Brugmann, Brussels, Belgium
[3] Univ Libre Bruxelles, Dept Radioisotopes, CHU Brugmann, Brussels, Belgium
[4] Katholieke Univ Leuven, Ctr Metab Bone Dis, Louvain, Belgium
[5] Catholic Univ Louvain, Dept Rheumatol, Mont Godinne Univ Hosp, B-1200 Brussels, Belgium
[6] Catholic Univ Louvain, Dept Rheumatol, St Luc Univ Hosp, B-1200 Brussels, Belgium
[7] Univ Ghent, Dept Rheumatol & Endocrinol, B-9000 Ghent, Belgium
[8] State Univ Gent, Dept Endocrinol, Ghent, Belgium
[9] Univ Libre Bruxelles, Dept Gynaecol Obstet, Brussels, Belgium
[10] Univ Liege, Dept Publ Hlth Epidemiol & Hlth Econ, Liege, Belgium
关键词
Bisphosphonate; Osteoporosis; Raloxifene; Strontium; Teriparatide; VITAMIN-D SUPPLEMENTATION; MONTHLY ORAL IBANDRONATE; VERTEBRAL FRACTURE RISK; CONTINUING OUTCOMES RELEVANT; INTRAVENOUS ZOLEDRONIC ACID; STRONTIUM RANELATE; MINERAL DENSITY; NONVERTEBRAL FRACTURES; BREAST-CANCER; PARATHYROID-HORMONE;
D O I
10.1007/s00198-010-1223-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Several drugs are available for the management of postmenopausal osteoporosis. This may, in daily practice, confuse the clinician. This manuscript offers an evidence-based update of previous treatment guidelines, with a critical assessment of the currently available efficacy data on all new chemical entities which were granted a marketing authorization. Osteoporosis is widely recognized as a major public health concern. The availability of new therapeutic agents makes clinical decision-making in osteoporosis more complex. Nation-specific guidelines are needed to take into consideration the specificities of each and every health care environment. The present manuscript is the result of a National Consensus, based on a systematic review and a critical appraisal of the currently available literature. It offers an evidence-based update of previous treatment guidelines, with the aim of providing clinicians with an unbiased assessment of osteoporosis treatment effect.
引用
收藏
页码:1657 / 1680
页数:24
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