Evidence-based guidelines for the pharmacological treatment of postmenopausal osteoporosis: a consensus document by the Belgian Bone Club

被引:86
作者
Body, J. -J. [2 ]
Bergmann, P. [3 ]
Boonen, S. [4 ]
Boutsen, Y. [5 ]
Devogelaer, J. -P. [6 ]
Goemaere, S. [7 ]
Kaufman, J. -M. [8 ]
Rozenberg, S. [9 ]
Reginster, J. -Y. [1 ,10 ]
机构
[1] CHU Ctr Ville, Bone & Cartilage Metab Res Unit, Policlin L BRULL, B-4020 Liege, Belgium
[2] Univ Libre Bruxelles, Dept Med, CHU Brugmann, Brussels, Belgium
[3] Univ Libre Bruxelles, Dept Radioisotopes, CHU Brugmann, Brussels, Belgium
[4] Katholieke Univ Leuven, Ctr Metab Bone Dis, Louvain, Belgium
[5] Catholic Univ Louvain, Dept Rheumatol, Mont Godinne Univ Hosp, B-1200 Brussels, Belgium
[6] Catholic Univ Louvain, Dept Rheumatol, St Luc Univ Hosp, B-1200 Brussels, Belgium
[7] Univ Ghent, Dept Rheumatol & Endocrinol, B-9000 Ghent, Belgium
[8] State Univ Gent, Dept Endocrinol, Ghent, Belgium
[9] Univ Libre Bruxelles, Dept Gynaecol Obstet, Brussels, Belgium
[10] Univ Liege, Dept Publ Hlth Epidemiol & Hlth Econ, Liege, Belgium
关键词
Bisphosphonate; Osteoporosis; Raloxifene; Strontium; Teriparatide; VITAMIN-D SUPPLEMENTATION; MONTHLY ORAL IBANDRONATE; VERTEBRAL FRACTURE RISK; CONTINUING OUTCOMES RELEVANT; INTRAVENOUS ZOLEDRONIC ACID; STRONTIUM RANELATE; MINERAL DENSITY; NONVERTEBRAL FRACTURES; BREAST-CANCER; PARATHYROID-HORMONE;
D O I
10.1007/s00198-010-1223-4
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Several drugs are available for the management of postmenopausal osteoporosis. This may, in daily practice, confuse the clinician. This manuscript offers an evidence-based update of previous treatment guidelines, with a critical assessment of the currently available efficacy data on all new chemical entities which were granted a marketing authorization. Osteoporosis is widely recognized as a major public health concern. The availability of new therapeutic agents makes clinical decision-making in osteoporosis more complex. Nation-specific guidelines are needed to take into consideration the specificities of each and every health care environment. The present manuscript is the result of a National Consensus, based on a systematic review and a critical appraisal of the currently available literature. It offers an evidence-based update of previous treatment guidelines, with the aim of providing clinicians with an unbiased assessment of osteoporosis treatment effect.
引用
收藏
页码:1657 / 1680
页数:24
相关论文
共 156 条
  • [1] Abrahamsen B, 2009, J BONE MINER RES, V24, P1095, DOI [10.1359/JBMR.081247, 10.1359/jbmr.081247]
  • [2] Fracture incidence and characterization in patients on osteoporosis treatment: The ICARO study
    Adami, Silvano
    Isaia, Giancarlo
    Luisetto, Giovanni
    Minisola, Salvatore
    Sinigaglia, Luigi
    Gentilella, Raffaella
    Agnusdei, Donato
    Iori, Nicoletta
    Nuti, Ranuccio
    [J]. JOURNAL OF BONE AND MINERAL RESEARCH, 2006, 21 (10) : 1565 - 1570
  • [3] Alekel DL, 2000, AM J CLIN NUTR, V72, P844
  • [4] Ipriflavone in the treatment of postmenopausal osteoporosis - A randomized controlled trial
    Alexandersen, P
    Toussaint, A
    Christiansen, C
    Devogelaer, JP
    Roux, C
    Fechtenbaum, J
    Gennari, C
    Reginster, JY
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (11): : 1482 - 1488
  • [5] The Pathogenesis of Bisphosphonate-Related Osteonecrosis of the Jaw: So Many Hypotheses, So Few Data
    Allen, Matthew R.
    Burr, David B.
    [J]. JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY, 2009, 67 (05) : 61 - 70
  • [6] [Anonymous], 1994, JAMA, V272, P1942
  • [7] Costs induced by hip fractures:: A prospective controlled study in Belgium
    Autier, P
    Haentjens, P
    Bentin, J
    Baillon, JM
    Grivegnée, AR
    Colson, MC
    Boonen, S
    [J]. OSTEOPOROSIS INTERNATIONAL, 2000, 11 (05) : 373 - 380
  • [8] Two to three years of hormone replacement treatment in healthy women have long-term preventive effects on bone mass and osteoporotic fractures:: the PERF study
    Bagger, YZ
    Tankó, LB
    Alexandersen, P
    Hansen, HB
    Mollgaard, A
    Ravn, P
    Qvist, P
    Kanis, JA
    Christiansen, C
    [J]. BONE, 2004, 34 (04) : 728 - 735
  • [9] Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants
    Bain, S. D.
    Jerome, C.
    Shen, V.
    Dupin-Roger, I.
    Ammann, P.
    [J]. OSTEOPOROSIS INTERNATIONAL, 2009, 20 (08) : 1417 - 1428
  • [10] In vitro effects of S12911-2 on osteoclast function and bone marrow macrophage differentiation
    Baron, R
    Tsouderos, Y
    [J]. EUROPEAN JOURNAL OF PHARMACOLOGY, 2002, 450 (01) : 11 - 17