Comparative reactivity of hydroxyketones and their derivatives in the reactions with N,S-nucleophiles

被引：4

作者：

Pulatov, E. Kh. ^{[1
]}

Isobaev, M. D. ^{[1
]}

Mavlonov, B. G. ^{[1
]}

Abdullaev, T. Kh. ^{[1
]}

机构：

[1] Acad Sci Republ Tajikistan, VI Nikitin Inst Chem, 299-2 Ul Aini, Dushanbe 734063, Tajikistan

来源：

RUSSIAN CHEMICAL BULLETIN | 2018年 / 67卷 / 06期

关键词：

monohalo- and dihalo-substituted acetylenic alcohols; oxyketones; thiosemicarbazide; thiocarbohydrazide; thiocarbamic acid;

D O I：

10.1007/s11172-018-2188-2

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reactions of thiosemicarbazide (TSC), thiocarbohydrazide, and hydrazine thiocarbamate with oxyketones, haloketones, and derivatives of acetylenic alcohols were studied. Thiadiazines bearing exocyclic thio and hydrazo groups were synthesized. Acetylenic alcohols react with TSC to give the corresponding thiazolidines. The reactions of halo derivatives of acetylenic alcohols with TSC are complicated by side reactions.

引用

页码：1106 / 1109

页数：4

共 12 条

[1] Borisova A. P., 2006, P INT C ORG CHEM ORG, P230
[2] Brandsma L., 2004, SYNTHESIS ACETYLENES
[3] Butyrskaya E.V., 2011, KOMPYUTERNAYA KHIMIY
[4] Frisch M., 2004, GAUSSIAN 03 REVISION, DOI DOI 10.1016/J.MOLSTRUC.2017.03.014
[5] PREPARATION OF T-ACETYLENIC CHLORIDES
HENNION, GF
BOISSELLE, AP
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1961, 26 (03) : 725 - &
[6] Behavior of benzoins and hydroxy ketones in acid media: 1. Reaction of 1-aryl-2-(2,5-dimethylthiophen-3-yl)-2-hydroxyethanones with thiols in trifluoroacetic acid
Krayushkin, MM
Lichitskii, BV
Mikhalev, AP
Dudinov, AA
Ivanov, SN
[J]. RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2005, 41 (01) : 87 - 90
[7] Total syntheses of the strobilurins G, M, and N
Kroiss, S
Steglich, W
[J]. TETRAHEDRON, 2004, 60 (22) : 4921 - 4929
[8] Light-induced stereospecific intramolecular [2+2]-cycloaddition of atropisomeric 3,4-dihydro-2-pyridones
Kumarasamy, Elango
Sivaguru, J.
[J]. CHEMICAL COMMUNICATIONS, 2013, 49 (39) : 4346 - 4348
[9] NAZAROV IN, 1959, ZH OBSHCH KHIM+, V29, P735
[10] Hydroxyketones in the thiadiazine cycle formation
Pulatov, E. Kh
Isobaev, M. J.
Mavlonov, B. G.
[J]. RUSSIAN CHEMICAL BULLETIN, 2016, 65 (10) : 2475 - 2478

← 1 2 →