Diagnostic Performance of Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio in Endometrioma

Introduction: To evaluate whether neutrophil/lymphocyte ratio (NLR) and platelet/lymphocyte ratio (PLR) have diagnostic value in endometrioma, which is a chronic inflammatory disease. Methods: A total of 187 patients who underwent surgery for adnexal mass, 97 patients diagnosed with endometrioma and 90 patients with benign cyst (corpus luteum, serous cysts or functional cysts), were included in this retrospective, comparative case series. NLR and PLR values obtained from preoperative complete blood count parameters were compared between the two groups. Results: There was no statistically significant difference between endometrioma and benign cyst groups regarding mean age (34.8 +/- 8.93 and 34.0 +/- 8.59 years, respectively, p=0.88). Fourteen point four percent (n=14) of the endometriomas were bilateral. The mean endometrioma size was 6.0 +/- 2.74 cm and 27.8% (n=27) of the endometriomas was found to be smaller than 5 cm. There was no significant difference between the endometrioma and the benign cyst group in terms of median NLR values (1.848 and 1.635, respectively, p=0.124). PLR median values were significantly higher in endometrioma group than in benign cyst group (128.77 and 114.69, respectively, p=0.015). NLR ratio was found to be statistically significantly higher in bilateral endometriomas compared to unilaterals. Conclusion: Although NLR was not found to be elevated in patients with endometrioma, it was found to be affected from bilaterality. PLR was found to be elevated in patients with endometrioma and not affected by the stage of the disease.