Mannose-binding lectin (MBL2) polymorphisms and inflammation in hypertensive patients

被引：2
|
作者：
Schreiber, R. [1 ]
Campos-Coelho, A. V. [2 ]
Brandao, L. [2 ]
Guimaraes, R. L. [2 ]
Kamada, A. J. [2 ]
Ferreira-Sae, M. C. [1 ]
Matos-Souza, J. R. [1 ]
Cipolli, J. A. [1 ]
de Lima-Filho, J. L. [2 ]
Crovella, S. [3 ]
Nadruz, W., Jr. [1 ]
机构：
[1] Univ Estadual Campinas, Dept Internal Med, Campinas, SP, Brazil
[2] Univ Fed Pernambuco, LIKA, Recife, PE, Brazil
[3] Univ Fed Pernambuco, Dept Genet, Recife, PE, Brazil
来源：
INTERNATIONAL JOURNAL OF IMMUNOGENETICS | 2011年 / 38卷 / 06期
关键词：
DEFICIENCY;
D O I：
10.1111/j.1744-313X.2011.01036.x
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
We investigated the possible role of Mannose binding lectin 2 (MBL2) functional polymorphisms in the prevalence of hypertension and hypertensive end-organ damage in 300 hypertensive patients and 313 normotensive individuals from Southern Brazil. Hypertensive subjects with MBL2 AO/OO genotypes presented lower C-reactive protein levels than AA individuals and consequently lower inflammatory status.
引用
收藏
页码：525 / 527
页数：3
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