The association between length of benzodiazepine use and sleep quality in older population

被引:23
作者
Beland, Sarah-Gabrielle [1 ,8 ]
Preville, Michel [2 ,3 ]
Dubois, Marie-France [2 ,4 ]
Lorrain, Dominique [4 ,5 ]
Voyer, Philippe [6 ,7 ]
Bosse, Cindy [2 ,3 ]
Grenier, Sebastien [3 ]
Moride, Yola [8 ]
机构
[1] Univ Montreal, Pharmaceut Sci Program, Montreal, PQ, Canada
[2] Univ Sherbrooke, Fac Med & Hlth Sci, Sherbrooke, PQ J1K 2R1, Canada
[3] Charles Lemoyne Hosp Res Ctr, Longueuil, PQ, Canada
[4] Sherbrooke Res Ctr Aging, Sherbrooke, PQ, Canada
[5] Univ Sherbrooke, Fac Human Sci, Sherbrooke, PQ J1K 2R1, Canada
[6] Univ Laval, Fac Nursing, Quebec City, PQ, Canada
[7] Univ Laval, Geriatr Res Unit, Quebec City, PQ, Canada
[8] Univ Montreal, Fac Pharm, Montreal, PQ H3C 3J7, Canada
基金
加拿大健康研究院;
关键词
benzodiazepines; older; sleep; Pittsburgh Sleep Quality Index; ELDERLY-PATIENTS; CHRONIC INSOMNIA; DOUBLE-BLIND; SELF-REPORT; ADULTS; RISK; DEPRESSION; DEMENTIA; DRUGS;
D O I
10.1002/gps.2623
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background: Sleep disturbances are frequently reported in the older adult population and benzodiazepines are the drugs most often prescribed to treat these problems. Nearly 25% of the older adult population uses these drugs and 83% of benzodiazepine users report sleep problems. Although the College des Medecins du Quebec suggests a maximum length of use of 3 months, according to most studies the mean length of benzodiazepine use is longer. The goal of this study was to document the association between length of benzodiazepine use and sleep quality as reported by adults 65 years older and over. Methods: Data used in this study came from the Seniors' Health Survey (ESA) conducted in a representative sample of the community-dwelling older population in Quebec, Canada. Inclusion criteria included the ability to speak and understand French. Data were analyzed using a structural equation modeling strategy. Results: Long-term benzodiazepine users were more likely to report poor sleep quality. Sleep quality of initial probable problematic sleepers tended to increase over 1 year but sleep quality in benzodiazepines users increased less rapidly than in non-users. Also, women were more likely to report using benzodiazepines and having poorer sleep quality. Conclusion: Longitudinal studies using incident cases of benzodiazepine use should be conducted to better determine the causal relationship between sleep quality and benzodiazepine use in the older population. Copyright (C) 2010 John Wiley & Sons, Ltd.
引用
收藏
页码:908 / 915
页数:8
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