Determination of psilocin and psilocybin using flow injection analysis with acidic potassium permanganate and tris(2,2′-bipyridyl) ruthenium(II) chemiluminescence detection respectively

被引：21
作者：
Anastos, N
Barnett, NW
Lewis, SW [1 ]
Gathergood, N
Scammells, PJ
Sims, DN
机构：
[1] Deakin Univ, Sch Biol & Chem Sci, Geelong, Vic 3217, Australia
[2] Monash Univ, Victorian Coll Pharm, Parkville, Vic 3052, Australia
[3] Forens Sci SA, Adelaide, SA 5000, Australia
来源：
TALANTA | 2005年 / 67卷 / 02期
关键词：
psilocin; psilocybin; flow injection analysis; chemiluminescence; synthesis; forensic analysis;
D O I：
10.1016/j.talanta.2004.11.038
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
A simple, rapid and sensitive method for the determination of psilocin and psilocybin is described. This is the first report on the determination of psilocin and psilocybin using flow injection analysis with acidic potassium permanganate and tris(2,2'-bipyridyl)ruthenium(II) chemiluminescence. The limits of detection (signal-to-noise ratio = 3) are 9 x 10(-10) M and 3 x 10(-10) M for psilocin and psilocybin, respectively. A concise synthetic route for psilocin in three steps from readily available starting materials is also described. The structures were elucidated on the basis of spectroscopic data. (c) 2005 Elsevier B.V. All rights reserved.
引用
收藏
页码：354 / 359
页数：6
相关论文
共 50 条
[1]   The determination of psilocin and psilocybin in hallucinogenic mushrooms by HPLC utilizing a dual reagent acidic potassium permanganate and tris(2,2′-bipyridyl)ruthenium(II) chemiluminescence detection system [J].
Anastos, N ;
Lewis, SW ;
Barnett, NW ;
Sims, DN .
JOURNAL OF FORENSIC SCIENCES, 2006, 51 (01) :45-51
[2]   Detection of pyrrolizidine alkaloids using flow analysis with both acidic potassium permanganate and tris(2,2′-bipyridyl)ruthenium(II) chemiluminescence [J].
Gorman, BA ;
Barnett, NW ;
Bos, R .
ANALYTICA CHIMICA ACTA, 2005, 541 (1-2) :119-124
[3]   Determination of proline in wine using flow injection analysis with tris(2,2′-bipyridyl)ruthenium(II) chemiluminescence detection [J].
Costin, JW ;
Barnett, NW ;
Lewis, SW .
TALANTA, 2004, 64 (04) :894-898
[4]   Flow injection chemiluminescence determination of cephalosporins in pharmaceutical preparations using tris (2,2′-bipyridyl) ruthenium (II)-potassium permanganate system [J].
Thongpoon, C ;
Liawruangrath, B ;
Liawruangrath, S ;
Wheatley, RA ;
Townshend, A .
ANALYTICA CHIMICA ACTA, 2005, 553 (1-2) :123-133
[5]   Flow-Injection Chemiluminescent Determination of Piroxicam Using Tris (2,2'-bipyridyl) Ruthenium(II)Potassium Permanganate System [J].
Yu, Fengshan ;
Chen, Fang ;
Zheng, Shishi ;
Chen, Lanhua ;
Cui, Man .
ANALYTICAL LETTERS, 2008, 41 (13) :2412-2423
[6]   Flow injection determination of thyroxine in pharmaceutical preparations using tris(2,2′-bipyridyl)ruthenium(III)-NADH chemiluminescence detection [J].
Waseem, Amir ;
Yaqoob, Mohammad ;
Nabi, Abdul .
TALANTA, 2007, 71 (01) :56-61
[7]   Chemiluminescence determination of tetracyclines using a tris(2,2′-bipyridine)ruthenium(II) and potassium permanganate system [J].
Han, HY ;
He, ZK ;
Zeng, Y .
ANALYTICAL SCIENCES, 1999, 15 (05) :467-470
[8]   Chemiluminescence Determination of Tetracyclines Using a Tris(2,2′-bipyridine)ruthenium(II) and Potassium Permanganate System [J].
Heyou Han ;
Zhike He ;
Yun’e Zeng .
Analytical Sciences, 1999, 15 :467-470
[9]   Flow Injection Determination of Lactate Using Immobilized Lactate Dehydrogenase Enzyme with Tris(2,2′-Bipyridyl)Ruthenium(III) Chemiluminescence Detection [J].
Rishi, Lubna ;
Yaqoob, Mohammad ;
Asghar, Mohammad ;
Nabi, Abdul ;
Munawar, Nusrat .
ANALYTICAL LETTERS, 2016, 49 (05) :654-664
[10]   Determination of iodide using flow injection with acidic potassium permanganate chemiluminescence detection [J].
Yaqoob, Mohammad ;
Atiq-ur-Rehman ;
Waseem, Amir ;
Nabi, Abdul .
LUMINESCENCE, 2006, 21 (04) :221-225
12345