Bidirectional Glenn and antegrade pulmonary blood flow:: Temporary or definitive palliation?

被引:47
作者
Calvaruso, Davide F. [1 ,2 ,3 ,4 ]
Rubino, Antonio [1 ,2 ,3 ,4 ]
Ocello, Salvatore [1 ,2 ,3 ,4 ]
Salviato, Nicoletta [1 ,2 ,3 ,4 ]
Guardi, Diego [1 ,2 ,3 ,4 ]
Petruccelli, David F. [1 ,2 ,3 ,4 ]
Cipriani, Adriano [1 ,2 ,3 ,4 ]
Fattouch, Khalil [1 ,2 ,3 ,4 ]
Agati, Salvatore [1 ,2 ,3 ,4 ]
Mignosa, Carmelo [1 ,2 ,3 ,4 ]
Zannini, Lucio [1 ,2 ,3 ,4 ]
Marcelletti, Carlo F. [1 ,2 ,3 ,4 ]
机构
[1] Osped Civ, Azienda Rilievo Nazl & Alta Specializzaz, Dept Pediat Cardiac Surg Marta & Milagros, I-90127 Palermo, Italy
[2] Osped S Vincenzo, Dept Pediat Cardiac Surg, Taormina, ME, Italy
[3] Univ Palermo, Dept Cardiac Surg, Palermo, Italy
[4] Osped Pediat, Ist Ricovero & Cura Carattere Sci, Ist Gaslini, Dept Pediat Cardiac Surg, Genoa, Italy
关键词
D O I
10.1016/j.athoracsur.2008.01.013
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. We sought to investigate the role of the bidirectional Glenn with antegrade pulmonary blood flow in the surgical history of children with univentricular hearts. Methods. A series of 246 patients, from three joint institutions, having univentricular heart with restricted but not critical pulmonary blood flow received a bidirectional cavopulmonary shunt with additional forward pulmonary blood flow. All patients have been studied according to their progression, or not, to Fontan operation. Two hundred and eight (84.5%) patients underwent bidirectional cavopulmonary anastomosis as primary palliation. Twenty patients (8.1%) with previous pulmonary artery banding were also enrolled in the study. Patients who had received additional pulmonary blood flow through a previous systemic to pulmonary artery shunt for the critical pulmonary blood flow were excluded. Results. No in-hospital death occurred. Follow-up was complete at 100%. Mean follow-up was 4.2 +/- 2.8 years range, 6 months to 7 years). During the observational period 73 (29.7%) patients, considered optimal candidates, underwent Fontan completion for increasing cyanosis and (or) hematocrit and (or) fatigue with exertion. Three patients expired after total cavopulmonary connection (3 of 73; 4.1% mortality rate). The remaining 173 (70.3%) patients are alive with initial palliation. All patients were still well palliated with an arterial oxygen saturation at rest about 90%. Conclusions. According to our experience and results, bidirectional Glenn with antegrade pulmonary blood flow may be an excellent temporary palliation prior to a Fontan operation, which can be performed at the onset of symptoms. Bidirectional Glenn may also be the best possible palliation for a suboptimal candidate for Fontan.
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页码:1389 / 1396
页数:8
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