High-Intensity Exercise and Mitochondrial Biogenesis: Current Controversies and Future Research Directions

被引:129
作者
Bishop, David J. [1 ,2 ]
Botella, Javier [1 ]
Genders, Amanda J. [1 ]
Lee, Matthew J-C. [1 ]
Saner, Nicholas J. [1 ]
Kuang, Jujiao [1 ]
Yan, Xu [1 ]
Granata, Cesare [3 ]
机构
[1] Victoria Univ, Inst Hlth & Sport, Melbourne, Vic, Australia
[2] Edith Cowan Univ, Sch Med & Hlth Sci, Joondalup, Australia
[3] Monash Univ, Dept Diabet, Cent Clin Sch, Melbourne, Vic, Australia
关键词
HUMAN SKELETAL-MUSCLE; GLYCOGEN DEPLETION PATTERN; PLASMA LACTATE PARAMETERS; TO-DAY CHANGES; PROTEIN-SYNTHESIS; MESSENGER-RNA; FIBER-TYPE; SPRINT-INTERVAL; RESISTANCE EXERCISE; OXIDATIVE CAPACITY;
D O I
10.1152/physiol.00038.2018
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
It is well established that different types of exercise can provide a powerful stimulus for mitochondrial biogenesis. However, there are conflicting findings in the literature, and a consensus has not been reached regarding the efficacy of high-intensity exercise to promote mitochondrial biogenesis in humans. The purpose of this review is to examine current controversies in the field and to highlight some important methodological issues that need to be addressed to resolve existing conflicts.
引用
收藏
页码:56 / 70
页数:15
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