High-Intensity Exercise and Mitochondrial Biogenesis: Current Controversies and Future Research Directions

被引:114
作者
Bishop, David J. [1 ,2 ]
Botella, Javier [1 ]
Genders, Amanda J. [1 ]
Lee, Matthew J-C. [1 ]
Saner, Nicholas J. [1 ]
Kuang, Jujiao [1 ]
Yan, Xu [1 ]
Granata, Cesare [3 ]
机构
[1] Victoria Univ, Inst Hlth & Sport, Melbourne, Vic, Australia
[2] Edith Cowan Univ, Sch Med & Hlth Sci, Joondalup, Australia
[3] Monash Univ, Dept Diabet, Cent Clin Sch, Melbourne, Vic, Australia
关键词
HUMAN SKELETAL-MUSCLE; GLYCOGEN DEPLETION PATTERN; PLASMA LACTATE PARAMETERS; TO-DAY CHANGES; PROTEIN-SYNTHESIS; MESSENGER-RNA; FIBER-TYPE; SPRINT-INTERVAL; RESISTANCE EXERCISE; OXIDATIVE CAPACITY;
D O I
10.1152/physiol.00038.2018
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
It is well established that different types of exercise can provide a powerful stimulus for mitochondrial biogenesis. However, there are conflicting findings in the literature, and a consensus has not been reached regarding the efficacy of high-intensity exercise to promote mitochondrial biogenesis in humans. The purpose of this review is to examine current controversies in the field and to highlight some important methodological issues that need to be addressed to resolve existing conflicts.
引用
收藏
页码:56 / 70
页数:15
相关论文
共 136 条
  • [1] Exercise and Regulation of Protein Metabolism
    Atherton, Philip J.
    Phillips, Bethan E.
    Wilkinson, Daniel J.
    [J]. MOLECULAR AND CELLULAR REGULATION OF ADAPTATION TO EXERCISE, 2015, 135 : 75 - 98
  • [2] Adaptations of skeletal muscle to exercise: rapid increase in the transcriptional coactivator PGC-1
    Baar, K
    Wende, AR
    Jones, TE
    Marison, M
    Nolte, LA
    Chen, M
    Kelly, DP
    Holloszy, JO
    [J]. FASEB JOURNAL, 2002, 16 (14) : 1879 - 1886
  • [3] Nutrition and the Adaptation to Endurance Training
    Baar, Keith
    [J]. SPORTS MEDICINE, 2014, 44 : 5 - 12
  • [4] Baldwin J, 2000, MED SCI SPORT EXER, V32, P1648
  • [5] Acute Exercise Remodels Promoter Methylation in Human Skeletal Muscle
    Barres, Romain
    Yan, Jie
    Egan, Brendan
    Treebak, Jonas Thue
    Rasmussen, Morten
    Fritz, Tomas
    Caidahl, Kenneth
    Krook, Anna
    O'Gorman, Donal J.
    Zierath, Juleen R.
    [J]. CELL METABOLISM, 2012, 15 (03) : 405 - 411
  • [6] Day-to-Day Changes in Muscle Protein Synthesis in Recovery From Resistance, Aerobic, and High-Intensity Interval Exercise in Older Men
    Bell, Kirsten E.
    Seguin, Christopher
    Parise, Gianni
    Baker, Steven K.
    Phillips, Stuart M.
    [J]. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 2015, 70 (08): : 1024 - 1029
  • [7] Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis
    Bergeron, R
    Ren, JM
    Cadman, KS
    Moore, IK
    Perret, P
    Pypaert, M
    Young, LH
    Semenkovich, CF
    Shulman, GI
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2001, 281 (06): : E1340 - E1346
  • [8] Relationship between plasma lactate parameters and muscle characteristics in female cyclists
    Bishop, D
    Jenkins, DG
    McEniery, M
    Carey, MF
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2000, 32 (06) : 1088 - 1093
  • [9] The relationship between plasma lactate parameters, Wpeak and 1-h cycling performance in women
    Bishop, D
    Jenkins, DG
    Mackinnon, LT
    [J]. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 1998, 30 (08) : 1270 - 1275
  • [10] Bishop D, 1998, J Sci Med Sport, V1, P171