Terlipressin infusion in catecholamine-resistant shock

被引:15
作者
Jolley, DH [1 ]
De Keulenaer, BL [1 ]
Potter, A [1 ]
Stephens, DP [1 ]
机构
[1] Royal Darwin Hosp, Intens Care Unit, Darwin, NT, Australia
关键词
shock; septic; refractory; cardiogenic; terlipressin; vasopressin;
D O I
10.1177/0310057X0303100532
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Catecholamine-resistant shock is not uncommon in intensive care. Bolus dose terlipressin (a vasopressin analogue) has been used successfully in this setting allowing cessation of other vasopressor agents. The relative vasopressin deficiency in combination with the restoration of the vascular tone (by blocking adenosine triphosphate potassium-sensitive channels) by exogenous vasopressin may be the explanation of these beneficial effects. We describe a case report where the use of a continuous terlipressin infusion was associated with a dramatic improvement. To our knowledge there have been no previous reports of the use of terlipressin by continuous infusion for the treatment of catecholamine-resistant shock.
引用
收藏
页码:560 / 564
页数:5
相关论文
共 21 条
[1]   Low-dose terlipressin improves systemic and splanchnic hemodynamics in fluid-challenged endotoxic rats [J].
Asfar, P ;
Pierrot, M ;
Veal, N ;
Moal, F ;
Oberti, F ;
Croquet, V ;
Douay, O ;
Gallois, Y ;
Saumet, JL ;
Alquier, P ;
Calès, P .
CRITICAL CARE MEDICINE, 2003, 31 (01) :215-220
[2]  
AUZINGER GM, 2002, CRIT CARE, V6, P61
[3]   DIRECT CARDIAC EFFECTS OF VASOPRESSIN AND THEIR REVERSAL BY A VASCULAR ANTAGONIST [J].
BOYLE, WA ;
SEGEL, LD .
AMERICAN JOURNAL OF PHYSIOLOGY, 1986, 251 (04) :H734-H741
[4]   Treatment of intraoperative refractory hypotension with terlipressin in patients chronically treated with an antagonist of the renin-angiotensin system [J].
Eyraud, D ;
Brabant, S ;
Nathalie, D ;
Fléron, MH ;
Gilles, G ;
Bertrand, M ;
Coriat, P .
ANESTHESIA AND ANALGESIA, 1999, 88 (05) :980-984
[5]  
GARNER WL, 1993, ANN PLAS SURG, V31, P78
[6]   EFFECTS OF ANGIOTENSIN, VASOPRESSIN, AND METHOXAMINE ON CARDIAC-FUNCTION AND BLOOD-FLOW DISTRIBUTION IN CONSCIOUS DOGS [J].
HEYNDRICKX, GR ;
BOETTCHER, DH ;
VATNER, SF .
AMERICAN JOURNAL OF PHYSIOLOGY, 1976, 231 (05) :1579-1587
[7]   The effects of vasopressin on hemodynamics and renal function in severe septic shock: a case series [J].
Holmes, CL ;
Walley, KR ;
Chittock, DR ;
Lehman, T ;
Russell, JA .
INTENSIVE CARE MEDICINE, 2001, 27 (08) :1416-1421
[8]   Vasopressin plus oxygen vs vasopressin alone in cirrhotic patients portal-hypertensive gastropathy: Effects on gastric mucosal haemodynamics and oxygenation [J].
Iwao, T ;
Toyonaga, A ;
Shigemori, H ;
Oho, K ;
Sumino, M ;
Sato, M ;
Tanikawa, K .
JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 1996, 11 (03) :216-222
[9]   EFFECTIVENESS OF TRIGLYCYL VASOPRESSIN IN PERSISTENT HEMATURIA ASSOCIATED WITH SICKLE-CELL HEMOGLOBIN [J].
JOHN, EG ;
SCHADE, SG ;
SPIGOS, DG ;
CORT, JH ;
ROSENTHAL, IM .
ARCHIVES OF INTERNAL MEDICINE, 1980, 140 (12) :1589-1593
[10]  
KLASCO RK, 2002, DRUGDEX SYSTEM