A rapid stereocontrolled synthesis of the 3a-hydroxy-pyrrolo[2,3-b]indole skeleton, a building block for 10b-hydroxy-pyrazino[1′,2′:1,5]pyrrolo[2,3-b]indole-1,4-diones

被引：53
|
作者：
Ley, SV [1 ]
Cleator, E [1 ]
Hewitt, PR [1 ]
机构：
[1] Univ Cambridge, Dept Chem, Cambridge CB2 1EW, England
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2003年 / 1卷 / 20期
关键词：
5-N-ACETYLARDEEMIN; OXYGENATION; DERIVATIVES; TRYPTOPHAN; AMAUROMINE;
D O I：
10.1039/b308288a
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A two-step selenocyclisation-oxidative deselenation sequence was used to establish the 3a-hydroxy-pyrrolo-[2,3-b]indole core; these tricycles were used as effective precursors to 10b-hydroxy-pyrazino[1',2' : 1,5]pyrrolo-[2,3-b]indole-1,4-diones.
引用
收藏
页码：3492 / 3494
页数：3
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