Synthesis and Exploitation of InP/ZnS Quantum Dots for Bioimaging

被引:1
作者
Massadeh, Salam [1 ]
Xu, Shu [1 ]
Nann, Thomas [1 ]
机构
[1] Univ E Anglia, Sch Chem Sci & Pharm, Norwich NR4 7TJ, Norfolk, England
来源
COLLOIDAL QUANTUM DOTS FOR BIOMEDICAL APPLICATIONS IV | 2009年 / 7189卷
关键词
Quantum Dots; silica; biolabelling; phase transfer; synthesis method; COLLOIDAL INP NANOCRYSTALS; NANOPARTICLES; PHOTOLUMINESCENCE; PARTICLES; SHELL;
D O I
10.1117/12.816892
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
Nano- and cytotoxicity becomes increasingly more important with an increasing number of potenital bio-medical applications for semiconductor Quantum Dots (QDs). Therefore, the frequently used CdSe-based QDs are unsuitable per-se, since cadmium is highly toxic heavy metal and may leach out of QDs. Cadmium-free QDs have not been available for a long time, because the synthesis of e.g. monodisperes and highly crystalline InP QDs caused many problems. We report on the synthesis of InP/ZnS QDs with optical properties similar to those displayed by typical CdSe/ZnS QDs. A major break-through has been reached by addition of zinc ions into the reaction mixture. Furthermore, the transfer of InP/ZnS QDs to water and their exploitation for bioanalytical applications are reported. It is shown that InP/ZnS QDs can be used to replace CdSe-based ones for almost any bio-medical application.
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页数:11
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