Spinal leptomeningeal oligodendrogliomatosis after resection of cerebral anaplastic oligodendoglioma with 1p19q Co-deletion - A case report

被引:0
作者
Andres, Molina Jaque Felipe A. [1 ]
Fouzia, Ziad [2 ]
Sami, Raunio [3 ]
机构
[1] Wellington Reg Hosp, Dept Neurosurg, Riddiford St, Wellington 6021, New Zealand
[2] Waikato Hosp, Dept Pathol, Hamilton, New Zealand
[3] Waikato Hosp, Dept Neurosurg, Hamilton, New Zealand
关键词
Oligodendrogliomatosis; Leptomeningial disease; Leptomeningeal dissemination;
D O I
10.1016/j.jocn.2020.01.017
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Anaplastic Oligodendroglioma has a better prognosis in the presence of 1p19q co-deletion and IDH-1 mutation but spinal leptomeningeal dissemination of cerebral anaplastic oligodendroglioma is a rare occurrence. We describe the case of a 47 year old man with spinal leptomeningeal dissemination eight months after resection of an anaplastic cerebral oligodendroglioma presenting with encephalitic features. We present the radiological, biochemical, intraoperative and histological features of this syndrome. Despite resolution of symptoms with corticosteroid treatment and favourable biochemical markers, prognosis remains poor when spinal leptomeningeal disease is present. (C) 2020 Elsevier Ltd. All rights reserved.
引用
收藏
页码:314 / 316
页数:3
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