Stem Cell Therapies for Cerebral Palsy and Autism Spectrum Disorder-A Systematic Review

被引：8

作者：

Paprocka, Justyna ^{[1
]}

Kaminiow, Konrad ^{[2
]}

Kozak, Sylwia ^{[2
]}

Sztuba, Karolina ^{[2
]}

Emich-Widera, Ewa ^{[1
]}

机构：

[1] Med Univ Silesia, Dept Pediat Neurol, Fac Med Sci Katowice, PL-40752 Katowice, Poland

[2] Med Univ Silesia, Fac Med Sci Katowice, Dept Pediat Neurol, Students Sci Soc, PL-40752 Katowice, Poland

来源：

BRAIN SCIENCES | 2021年 / 11卷 / 12期

关键词：

stem cell therapy; cerebral palsy; autism spectrum disorder; UMBILICAL-CORD BLOOD; GROSS MOTOR FUNCTION; MESENCHYMAL STROMAL CELLS; OXIDATIVE STRESS; YOUNG-CHILDREN; BRAIN; TRANSPLANTATION; MECHANISMS; SAFETY; INFUSION;

D O I：

10.3390/brainsci11121606

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Autism spectrum disorder (ASD) and cerebral palsy (CP) are some of the most common neurodevelopmental diseases. They have multifactorial origin, which means that each case may manifest differently from the others. In patients with ASD, symptoms associated with deficits in social communication and characteristic, repetitive types of behaviors or interests are predominant, while in patients with CP, motor disability is diagnosed with accompanying cognitive impairment of various degrees. In order to minimize their adverse effects, it is necessary to promptly diagnose and incorporate appropriate management, which can significantly improve patient quality of life. One of the therapeutic possibilities is stem cell therapy, already known from other branches of medicine, with high hopes for safe and effective treatment of these diseases. Undoubtedly, in the future we will have to face the challenges that will arise due to the still existing gaps in knowledge and the heterogeneity of this group of patients. The purpose of this systematic review is to summarize briefly the latest achievements and advances in stem cell therapy for ASD and CP.

引用

页数：18