Synthesis and antimicrobial activities of thiadiazole containing quinoline derivatives

被引：0

作者：

Dayananda, P. ^{[1
]}

Nayak, Janardhana ^{[2
,3
]}

D'Souza, Vineetha Telma ^{[3
,4
]}

机构：

[1] PU Coll, Dept Chem Excellent Sci & Commerce, Moodbidri 574227, Mangaluru, India

[2] NMAM Inst Technol, Dept Chem, Nitte 574110, India

[3] VTU, Belagavi, India

[4] MITE, Dept Chem, Moodbidri 574225, Mangaluru, India

来源：

INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY | 2021年 / 60卷 / 04期

关键词：

Quinoline; thiadiazole; thiourea; antibacterial; antifungal; ANTITUBERCULOSIS;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel series of 1-[(substituted 2-chloroquinolin-3-yOmethylidene]-3-[substituted-5-phenyl-1,3,4-thiadiazol-2-yl] thioureas have been synthesized by acid catalyzed reaction between the 1-(5-substitued phenyl-1,3,4-thiadiazol-2-yl) thioureas and 6-substituted-2-chloro-3-formyl quinolines. The structures of these compounds have been confirmed by spectral techniques like IR, H-1 NMR and mass spectroscopy. The new compounds have been screened for their antibacterial and antifungal activity studies. Most of the compounds show good activity comparable with that of the standard drugs.

引用

页码：633 / 638

页数：6

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