An instructive case of amlodipine-induced reversible granulomatous CD30+ T-cell pseudolymphoma

被引：3

作者：

Cheong, Kah Wai ^{[1
]}

Lim, Gareth Zigui ^{[1
]}

Tan, Kong Bing ^{[2
,3
]}

Lim, Joel Hua-Liang ^{[4
]}

机构：

[1] Natl Univ Hlth Syst, Tan Tock Seng Hosp, Singapore, Singapore

[2] Natl Univ Hlth Syst, Dept Pathol, Singapore, Singapore

[3] Natl Univ Singapore, Singapore, Singapore

[4] Natl Skin Ctr, Singapore, Singapore

来源：

AUSTRALASIAN JOURNAL OF DERMATOLOGY | 2020年 / 61卷 / 03期

关键词：

amlodipine; CD30+lymphoproliferative disorder; cutaneous T cell lymphoma; drug-associated reversible granulomatous T-cell dyscrasia; drug-induced pseudolymphoma; eosinophilia; interstitial granulomatous drug reaction; mycosis fungoides;

D O I：

10.1111/ajd.13240

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

We report an unusual case of drug-associated granulomatous CD30(+) T-cell pseudolymphoma secondary to amlodipine. A 55-year-old Chinese man presented with a 6-month eruption of disseminated erythematous dermal papulonodules and annular infiltrated plaques over his neck and limbs symmetrically. Histopathology revealed a perivascular and interstitial infiltrate of histiocytes, eosinophils and morphologically normal lymphocytes associated with CD30 expression. The eruption improved rapidly after discontinuation of amlodipine and did not recur.

引用

页码：E346 / E350

页数：5

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