Dimeric Manganese-Catalyzed Direct Nucleophilic Addition of C(sp2)-H Bonds to Inert Aldehydes

被引：5

作者：

Liu, Hongxin ^{[1
]}

Peng, Junqin ^{[1
]}

Li, Bin ^{[1
]}

Wang, Baiquan ^{[1
,2
]}

机构：

[1] Nankai Univ, Coll Chem, State Key Lab Elemento Organ Chem, Coll Chem, Tianjin 300071, Peoples R China

[2] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2022年 / 87卷 / 21期

基金：

中国国家自然科学基金;

关键词：

C-H BONDS; DIRECT HYDROXYMETHYLATION; CLEAVAGE; INDOLINES; ALCOHOLS; ARYLATION;

D O I：

10.1021/acs.joc.2c01908

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient direct nucleophilic addition reaction of C(sp2)-H bonds to aldehydes catalyzed by a dimeric manganese has been developed. This reaction has a broad range of substrates, and high yields were also obtained with inert aliphatic aldehydes as substrates. A dimeric Mn2(CO)8Br2 was proven to be a more efficient catalyst precursor than the monomeric Mn(CO)5Br.

引用

页码：14487 / 14495

页数：9

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