New triterpenoid glycosides from Centella asiatica

被引：25
作者：
Jiang, ZY [1 ]
Zhang, XM [1 ]
Zhou, J [1 ]
Chen, JJ [1 ]
机构：
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Yunnan, Peoples R China
来源：
HELVETICA CHIMICA ACTA | 2005年 / 88卷 / 02期
关键词：
D O I：
10.1002/hlca.200590011
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Four new triterpenoid glycosides named asiaticoside C (1), D (2), E (3), and F (4) were isolated from the BuOH fraction of the EtOH extract of whole plants of Centella asiatica, together with three known compounds, asiaticoside (5), madecassoside (6), and schelfuroside B (7). Based on FAB-MS, IR, H-1- and C-13-NMR, and 2D-NMR data (HMQC, HMBC, COSY), the structures of the new compounds were determined as (2alpha,3beta,4alpha)-23-(acetyloxy)-2,3-dihydroxyurs-12-en-28-oic acid O-alpha-L-rhamnopyranosyl-(1-->4)-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester (1), (2alpha,3beta)-2,3-dihydroxyurs-12-en-28-oic acid O-alpha-L-rhamnopyranosyl-(1-->4)-O-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester (2), asiatic acid 6-O-beta-D-glycopyranosyl-beta-D-glucopyranosyl ester (3), (3beta,4alpha)-3,23-dihydroxyurs-12-en-28-oic acid O-alpha-L-rhamnopyranosyl-(1-->4)-0-beta-D-glucopyranosyl-(1-->6)-beta-D-glucopyranosyl ester (4).
引用
收藏
页码：297 / 303
页数：7
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