The research progress of LncRNA involved in the regulation of inflammatory diseases

被引：84

作者：

Liao, Kaili ^{[1
,3
]}

Xu, Jiasheng ^{[2
]}

Yang, Weiming ^{[1
,3
]}

You, Xiahong ^{[1
,3
]}

Zhong, Qionghui ^{[1
,3
]}

Wang, Xiaozhong ^{[1
,3
]}

机构：

[1] Nanchang Univ, Affiliated Hosp 2, Dept Clin Lab, Nanchang, Jiangxi, Peoples R China

[2] Nanchang Univ, Affiliated Hosp 2, Dept Vasc Surg, Nanchang, Jiangxi, Peoples R China

[3] Jiangxi Prov Key Lab Lab Med, Nanchang, Jiangxi, Peoples R China

来源：

MOLECULAR IMMUNOLOGY | 2018年 / 101卷

关键词：

Inflammatory disease; Long non-coding RNA; Inflammation; Inflammatory bowel diseases; LONG NONCODING RNA; DOWN-REGULATION; SMOOTH-MUSCLE; EXPRESSION; APOPTOSIS; TRANSCRIPTION; OVEREXPRESSION; LANDSCAPE; BARRIER; PROFILE;

D O I：

10.1016/j.molimm.2018.05.030

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Long non-coding RNA (IncRNA)is a non-coding RNA which lacks a complete open reading frame(ORF) and plays an important role in biological processes such as cell proliferation,differentiation and apoptosis. At present,the expression of IncRNA has been found to be abnormal in inflammatory reaction and inflammatory diseases. It might be involved in the development and progression of inflammatory diseases by regulating the expression of multiple genes and activation of signaling pathways. This article overviewed the progress in study on relationship between lncRNA and inflammatory diseases.

引用

页码：182 / 188

页数：7

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