Overlapping Key Populations and HIV Transmission in Tijuana, Mexico: A Modelling Analysis of Epidemic Drivers

被引：8

作者：

Fraser, Hannah ^{[1
]}

Borquez, Annick ^{[2
]}

Stone, Jack ^{[1
]}

Abramovitz, Daniela ^{[2
]}

Brouwer, Kimberly C. ^{[2
]}

Goodman-Meza, David ^{[3
]}

Hickman, Matthew ^{[1
]}

Patterson, Thomas L. ^{[2
]}

Silverman, Jay ^{[2
]}

Smith, Laramie ^{[2
]}

Strathdee, Steffanie A. ^{[2
]}

Martin, Natasha K. ^{[1
,2
]}

Vickerman, Peter ^{[1
]}

机构：

[1] Univ Bristol, Populat Hlth Sci, Bristol Med Sch, Oakfield House, Bristol BS8 2BN, Avon, England

[2] Univ Calif San Diego, Sch Med, San Diego, CA 92103 USA

[3] Univ Calif Los Angels, David Geffen Sch Med, Los Angeles, CA USA

来源：

AIDS AND BEHAVIOR | 2021年 / 25卷 / 11期

关键词：

Mathematical modelling; People who inject drugs; Female sex workers; Men who have sex with men; Mexico; FEMALE SEX WORKERS; PREEXPOSURE PROPHYLAXIS; ANTIRETROVIRAL THERAPY; INFECTION; BORDER; RISK; METAANALYSIS; PREVENTION; PEOPLE; IMPACT;

D O I：

10.1007/s10461-021-03361-2

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Tijuana, Mexico, has a concentrated HIV epidemic among overlapping key populations (KPs) including people who inject drugs (PWID), female sex workers (FSW), their male clients, and men who have sex with men (MSM). We developed a dynamic HIV transmission model among these KPs to determine the extent to which their unmet prevention and treatment needs is driving HIV transmission. Over 2020-2029 we estimated the proportion of new infections acquired in each KP, and the proportion due to their unprotected risk behaviours. We estimate that 43.7% and 55.3% of new infections are among MSM and PWID, respectively, with FSW and their clients making-up < 10% of new infections. Projections suggest 93.8% of new infections over 2020-2029 will be due to unprotected sex between MSM or unsafe injecting drug use. Prioritizing interventions addressing sexual and injecting risks among MSM and PWID are critical to controlling HIV in Tijuana.

引用

页码：3814 / 3827

页数：14

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