GPIHBP1: Lipoprotein Lipase's Ticket to Ride

被引:8
作者
Fisher, Edward A. [1 ]
机构
[1] NYU, Sch Med, Marc & Ruti Bell Program Vasc Biol, New York, NY 10016 USA
关键词
CHYLOMICRONEMIA; RECEPTOR;
D O I
10.1016/j.cmet.2010.06.005
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
The mechanism of lipoprotein lipase (LPL) transport from muscle and fat cells to the luminal (apical) surface of capillaries, where it hydrolyses lipoprotein triglycerides, has remained undefined. In this issue, Davies et al. (2010) report that GPIHBP1 is required for LPL transcytosis from the basolateral to apical capillary endothelial surface.
引用
收藏
页码:1 / 2
页数:2
相关论文
共 9 条
[1]   Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons [J].
Beigneux, Anne P. ;
Davies, Brandon S. J. ;
Gin, Peter ;
Weinstein, Michael M. ;
Farber, Emily ;
Qiao, Xin ;
Peale, Franklin ;
Bunting, Stuart ;
Walzem, Rosemary L. ;
Wong, Jinny S. ;
Blaner, William S. ;
Ding, Zhi-Ming ;
Melford, Kristan ;
Wongsiriroj, Nuttaporn ;
Shu, Xiao ;
de Sauvage, Fred ;
Ryan, Robert O. ;
Fong, Loren G. ;
Bensadoun, Andre ;
Young, Stephen G. .
CELL METABOLISM, 2007, 5 (04) :279-291
[2]   Chylomicronemia With a Mutant GPIHBP1 (Q115P) That Cannot Bind Lipoprotein Lipase [J].
Beigneux, Anne P. ;
Franssen, Remco ;
Bensadoun, Andre ;
Gin, Peter ;
Melford, Kristan ;
Peter, Jorge ;
Walzem, Rosemary L. ;
Weinstein, Michael M. ;
Davies, Brandon S. J. ;
Kuivenhoven, Jan A. ;
Kastelein, John J. P. ;
Fong, Loren G. ;
Dallinga-Thie, Geesje M. ;
Young, Stephen G. .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2009, 29 (06) :956-U447
[3]   GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries [J].
Davies, Brandon S. J. ;
Beigneux, Anne P. ;
Barnes, Richard H., II ;
Tu, Yiping ;
Gin, Peter ;
Weinstein, Michael M. ;
Nobumori, Chika ;
Nyren, Rakel ;
Goldberg, Ira ;
Olivecrona, Gunilla ;
Bensadoun, Andre ;
Young, Stephen G. ;
Fong, Loren G. .
CELL METABOLISM, 2010, 12 (01) :42-52
[4]   Caveolae and transcytosis in endothelial cells: role in atherosclerosis [J].
Frank, Philippe G. ;
Pavlides, Stephanos ;
Lisanti, Michael P. .
CELL AND TISSUE RESEARCH, 2009, 335 (01) :41-47
[5]   Chylomicronemia With Low Postheparin Lipoprotein Lipase Levels in the Setting of GPIHBP1 Defects [J].
Franssen, Remco ;
Young, Stephen G. ;
Peelman, Frank ;
Hertecant, Jozef ;
Sierts, Jeroen A. ;
Schimmel, Alinda W. M. ;
Bensadoun, Andre ;
Kastelein, John J. P. ;
Fong, Loren G. ;
Dallinga-Thie, Geesje M. ;
Beigneux, Anne P. .
CIRCULATION-CARDIOVASCULAR GENETICS, 2010, 3 (02) :169-178
[6]   NORMAL PLASMA-LIPOPROTEINS AND FERTILITY IN GENE-TARGETED MICE HOMOZYGOUS FOR A DISRUPTION IN THE GENE ENCODING VERY-LOW-DENSITY LIPOPROTEIN RECEPTOR [J].
FRYKMAN, PK ;
BROWN, MS ;
YAMAMOTO, T ;
GOLDSTEIN, JL ;
HERZ, J .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1995, 92 (18) :8453-8457
[7]   Transcytosis of lipoprotein lipase across cultured endothelial cells requires both heparan sulfate proteoglycans and the very low density lipoprotein receptor [J].
Obunike, JC ;
Lutz, EP ;
Li, ZH ;
Paka, L ;
Katopodis, T ;
Strickland, DK ;
Kozarsky, KF ;
Pillarisetti, S ;
Goldberg, IJ .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (12) :8934-8941
[8]   Mutation of conserved cysteines in the Ly6 domain of GPIHBP1 in familial chylomicronemia [J].
Olivecrona, Gunilla ;
Ehrenborg, Ewa ;
Semb, Henrik ;
Makoveichuk, Elena ;
Lindberg, Anna ;
Hayden, Michael R. ;
Gin, Peter ;
Davies, Brandon S. J. ;
Weinstein, Michael M. ;
Fong, Loren G. ;
Beigneux, Anne P. ;
Young, Stephen G. ;
Olivecrona, Thomas ;
Hernell, Olle .
JOURNAL OF LIPID RESEARCH, 2010, 51 (06) :1535-1545
[9]   Some Things Just Have to Be Done In Vivo GPIHBP1, Caloric Delivery, and the Generation of Remnant Lipoproteins [J].
Williams, Kevin Jon .
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2009, 29 (06) :792-795