Absolute Cardiovascular Disease Risk Assessed in Old Age Predicts Disability and Mortality: A Retrospective Cohort Study of Community-Dwelling Older Adults
被引:8
|
作者:
Makino, Keitaro
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Japan & Japan Soc Promot Sci, Chiyoda Ku, Tokyo, JapanNatl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Makino, Keitaro
[1
,3
]
Lee, Sangyoon
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Lee, Sangyoon
[1
]
Bae, Seongryu
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Bae, Seongryu
[1
]
Chiba, Ippei
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Chiba, Ippei
[1
]
Harada, Kenji
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Harada, Kenji
[1
]
Katayama, Osamu
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Katayama, Osamu
[1
]
Shinkai, Yohei
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, JapanNatl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Shinkai, Yohei
[1
]
Shimada, Hiroyuki
论文数: 0引用数: 0
h-index: 0
机构:
Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Obu City, Aichi, JapanNatl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
Shimada, Hiroyuki
[2
]
机构:
[1] Natl Ctr Geriatr & Gerontol, Dept Prevent Gerontol, Ctr Gerontol & Social Sci, 7-430 Morioka Cho, Obu City, Aichi 4748511, Japan
[2] Natl Ctr Geriatr & Gerontol, Ctr Gerontol & Social Sci, Obu City, Aichi, Japan
[3] Japan & Japan Soc Promot Sci, Chiyoda Ku, Tokyo, Japan
来源:
JOURNAL OF THE AMERICAN HEART ASSOCIATION
|
2021年
/
10卷
/
24期
Background Evidence is limited on the predictive validity of absolute cardiovascular disease (CVD) risk, estimated by multivariable assessments in old age, for disability and mortality. We aimed to examine the longitudinal associations of absolute CVD risk assessed using region-specific risk estimation charts with disability and mortality among community-dwelling people aged >= 65 years. Methods and Results This retrospective cohort study included 7456 community-dwelling people aged >= 65 years (mean age, 73.7 years) without CVD and functional decline at baseline. They lived in either Obu City or Midori Ward of Nagoya City, Aichi Prefecture, Japan. We estimated absolute CVD risk using the revised World Health Organization CVD risk estimation charts and stratified risk levels into 3 categories: low (<10%), mid (10% to <20%), and high (>= 20%). We followed up the functional disability incidence and all-cause mortality monthly for 5 years. The prevalence of each CVD risk level based on the laboratory-based model was as follows: low CVD risk, 1096 (14.7%); mid CVD risk, 5510 (73.9%); and high CVD risk, 850 (11.4%). During follow-up, the incidence rates of disability and mortality were 33.4 per 1000 and 12.4 per 1000 person-years, respectively. Cox regression analysis showed that the adjusted hazard ratios (95% CIs) for disability incidence were 1.32 (1.13-1.56) and 1.44 (1.18-1.77) in mid and high CVD risk levels, respectively (reference: low CVD risk level); for mortality incidence, they were 1.53 (1.16-2.01) and 2.02 (1.45-2.80) in mid and high CVD risk levels, respectively (reference: low CVD risk level). Conclusions Absolute CVD risk was associated with both disability and mortality in people aged >= 65 years. Estimated CVD risk levels may be useful surrogate markers for disability and mortality risks even when assessed in old age.
机构:
Ageo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, JapanAgeo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, Japan
Otsuka, Hiromasa
Kobayashi, Hiroki
论文数: 0引用数: 0
h-index: 0
机构:
Nihon Univ, Div Nephrol Hypertens & Endocrinol, Dept Internal Med, Sch Med,Itabashi Ku, 30-1 Oyaguchikami Machi, Tokyo 1738610, JapanAgeo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, Japan
Kobayashi, Hiroki
Suzuki, Kiyozumi
论文数: 0引用数: 0
h-index: 0
机构:
Ageo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, JapanAgeo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, Japan
Suzuki, Kiyozumi
Hayashi, Yuta
论文数: 0引用数: 0
h-index: 0
机构:
Sasaki Fdn Kyoundo Hosp, Div Internal Med, Tokyo, JapanAgeo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, Japan
Hayashi, Yuta
Ikeda, Jin
论文数: 0引用数: 0
h-index: 0
机构:
Nihon Univ, Sch Internal Med, Dept Internal Med, Div Gen Med, Tokyo, JapanAgeo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, Japan
Ikeda, Jin
Kushimoto, Masaru
论文数: 0引用数: 0
h-index: 0
机构:
Nihon Univ, Sch Internal Med, Dept Internal Med, Div Gen Med, Tokyo, JapanAgeo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, Japan
Kushimoto, Masaru
Hara, Motohiko
论文数: 0引用数: 0
h-index: 0
机构:
Saitama Prefectural Univ, Sch Hlth & Social Serv, Dept Nursing, Saitama, Japan
Teikyo Univ, Dept Rehabil, Sch Med, Tokyo, JapanAgeo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, Japan
Hara, Motohiko
Abe, Masanori
论文数: 0引用数: 0
h-index: 0
机构:
Nihon Univ, Div Nephrol Hypertens & Endocrinol, Dept Internal Med, Sch Med,Itabashi Ku, 30-1 Oyaguchikami Machi, Tokyo 1738610, JapanAgeo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, Japan
Abe, Masanori
Kato, Kimitoshi
论文数: 0引用数: 0
h-index: 0
机构:
Nihon Univ, Sch Internal Med, Dept Internal Med, Div Gen Med, Tokyo, JapanAgeo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, Japan
Kato, Kimitoshi
Soma, Masayoshi
论文数: 0引用数: 0
h-index: 0
机构:
Nihon Univ, Sch Internal Med, Dept Internal Med, Div Gen Med, Tokyo, Japan
Sasaki Fdn Kyoundo Hosp, Div Internal Med, Tokyo, JapanAgeo Cent Gen Hosp, Dept Emergency Room & Gen Med, Saitama, Japan
机构:
Tongji Univ, Sport & Hlth Res Ctr, Dept Phys Educ, 1239 Siping Rd, Shanghai 200092, Peoples R ChinaTongji Univ, Sport & Hlth Res Ctr, Dept Phys Educ, 1239 Siping Rd, Shanghai 200092, Peoples R China
Chen, Tao
Honda, Takanori
论文数: 0引用数: 0
h-index: 0
机构:
Kyushu Univ, Grad Sch Med Sci, Dept Epidemiol & Publ Hlth, Higashi Ku, 3-1-1 Maidashi, Fukuoka, Fukuoka 8128582, JapanTongji Univ, Sport & Hlth Res Ctr, Dept Phys Educ, 1239 Siping Rd, Shanghai 200092, Peoples R China
Honda, Takanori
Chen, Sanmei
论文数: 0引用数: 0
h-index: 0
机构:
Hiroshima Univ, Grad Sch Biomed & Hlth Sci, Dept Global Hlth Nursing, 1-2-3 Kasumi, Hiroshima 7348553, JapanTongji Univ, Sport & Hlth Res Ctr, Dept Phys Educ, 1239 Siping Rd, Shanghai 200092, Peoples R China
Chen, Sanmei
Kishimoto, Hiro
论文数: 0引用数: 0
h-index: 0
机构:
Kyushu Univ, Fac Arts & Sci, Nishi Ku, 744 Motooka, Fukuoka, Fukuoka 8190395, JapanTongji Univ, Sport & Hlth Res Ctr, Dept Phys Educ, 1239 Siping Rd, Shanghai 200092, Peoples R China
Kishimoto, Hiro
Kumagai, Shuzo
论文数: 0引用数: 0
h-index: 0
机构:
Dong A Univ, Inst Convergence Bio Health, 37 Nakdong daero 550 Beon Gil, Busan 49315, South Korea
Kumagai Inst Hlth Policy, 4-47-1 Hiratadai, Kasuga, Fukuoka 8160812, JapanTongji Univ, Sport & Hlth Res Ctr, Dept Phys Educ, 1239 Siping Rd, Shanghai 200092, Peoples R China
Kumagai, Shuzo
Narazaki, Kenji
论文数: 0引用数: 0
h-index: 0
机构:
Fukuoka Inst Technol, Ctr Liberal Arts, Higashi Ku, 3-30-1 Wajiro Higashi, Fukuoka, Fukuoka 8110295, JapanTongji Univ, Sport & Hlth Res Ctr, Dept Phys Educ, 1239 Siping Rd, Shanghai 200092, Peoples R China
机构:
Rush Univ, Med Ctr, Dept Cell & Mol Med, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Dept Orthoped Surg, Chicago, IL 60612 USARush Univ, Med Ctr, Dept Cell & Mol Med, Chicago, IL 60612 USA
Ross, Ryan D.
Shah, Raj C.
论文数: 0引用数: 0
h-index: 0
机构:
Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Dept Family Med, Chicago, IL 60612 USARush Univ, Med Ctr, Dept Cell & Mol Med, Chicago, IL 60612 USA
Shah, Raj C.
Leurgans, Sue E.
论文数: 0引用数: 0
h-index: 0
机构:
Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USARush Univ, Med Ctr, Dept Cell & Mol Med, Chicago, IL 60612 USA
Leurgans, Sue E.
Buchman, Aron S.
论文数: 0引用数: 0
h-index: 0
机构:
Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USARush Univ, Med Ctr, Dept Cell & Mol Med, Chicago, IL 60612 USA
Buchman, Aron S.
Bennett, David A.
论文数: 0引用数: 0
h-index: 0
机构:
Rush Univ, Med Ctr, Rush Alzheimers Dis Ctr, Chicago, IL 60612 USA
Rush Univ, Med Ctr, Dept Neurol Sci, Chicago, IL 60612 USARush Univ, Med Ctr, Dept Cell & Mol Med, Chicago, IL 60612 USA
机构:
INSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Univ Paris 05, UMR S970, Paris, FranceINSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Plichart, Matthieu
Barberger-Gateau, Pascale
论文数: 0引用数: 0
h-index: 0
机构:
INSERM, U897, Bordeaux, France
Univ Bordeaux 2, F-33076 Bordeaux, FranceINSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Barberger-Gateau, Pascale
Tzourio, Christophe
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris 06, INSERM, U708, Paris, FranceINSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Tzourio, Christophe
Amouyel, Philippe
论文数: 0引用数: 0
h-index: 0
机构:
Inst Pasteur, INSERM, U744, F-59019 Lille, France
Univ Lille 2, Lille, FranceINSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Amouyel, Philippe
Peres, Karine
论文数: 0引用数: 0
h-index: 0
机构:
INSERM, U897, Bordeaux, France
Univ Bordeaux 2, F-33076 Bordeaux, FranceINSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Peres, Karine
Ritchie, Karen
论文数: 0引用数: 0
h-index: 0
机构:
INSERM, U888, Montpellier, France
Univ Montpellier I, IFR76, Montpellier, FranceINSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Ritchie, Karen
Jouven, Xavier
论文数: 0引用数: 0
h-index: 0
机构:
INSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Hop Europeen Georges Pompidou, Assistance Publ Hop Paris, Paris, FranceINSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Jouven, Xavier
Ducimetiere, Pierre
论文数: 0引用数: 0
h-index: 0
机构:
INSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, FranceINSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Ducimetiere, Pierre
Empana, Jean-Philippe
论文数: 0引用数: 0
h-index: 0
机构:
INSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France
Univ Paris 05, UMR S970, Paris, FranceINSERM, U970, Paris Cardiovasc Res Ctr PARCC, F-75015 Paris, France