Incidence of and risk factors for pre-operative deep venous thrombosis in geriatric intertrochanteric fracture patients

被引:21
作者
Zhao, Kuo [1 ,2 ,3 ]
Wang, Zhongzheng [1 ,2 ,3 ]
Tian, Siyu [1 ,2 ,3 ]
Hou, Zhiyong [1 ,2 ,3 ,4 ]
Chen, Wei [1 ,2 ,3 ]
Zhang, Yingze [1 ,2 ,3 ,4 ,5 ]
机构
[1] Hebei Med Univ, Dept Orthopaed Surg, Hosp 3, 139 Ziqiang Rd, Shijiazhuang, Hebei, Peoples R China
[2] Key Lab Biomech Hebei Prov, Shijiazhuang 050051, Hebei, Peoples R China
[3] Orthopaed Res Inst Hebei Prov, Shijiazhuang 050051, Hebei, Peoples R China
[4] Hebei Med Univ, NHC Key Lab Intelligent Orthopaed Equipment, Hosp 3, Shijiazhuang, Hebei, Peoples R China
[5] Chinese Acad Engn, Beijing 10088, Peoples R China
基金
国家重点研发计划;
关键词
Hip fracture; VET; Pre-operative interval; Hypoproteinemia; Medical comorbidities; HIP FRACTURE; VEIN THROMBOSIS; D-DIMER; PROGNOSTIC IMPACT; ELDERLY-PATIENTS; SURGICAL DELAY; SURGERY; THROMBOEMBOLISM; PREVALENCE; DIAGNOSIS;
D O I
10.1007/s00264-021-05215-x
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Purpose The purpose of this prospective study was to investigate the pre-operative incidence of and risk factors for deep venous thrombosis (DVT) in geriatric intertrochanteric fractures to help facilitate the peri-operative management of them. Materials and methods Data of 1515 geriatric intertrochanteric fracture patients were extracted from a prospective intertrochanteric fractures database according to the inclusion criteria and exclusion criteria. The demographics, fracture characteristics, and pre-operative laboratory indicators of patients were evaluated statistically. Results The incidence of pre-operative DVT was 10.2% (155 in 1360 patients) in the present study. The rates of proximal DVT, distal DVT, and mixed DVT were 18.1% (28 patients), 56.8% (88 patients), and 25.2% (39 patients), respectively. The percentages of DVT developing in the affected limb, uninjured limb, and bilateral limbs were 74.2% (115 in 55 patients), 16.8% (26 in 155 patients), and 9% (14 in 155 patients), respectively. After the multivariable analysis, the time from injury to surgery (TIS) > 4 days [odds ratio (OR) = 1.870, p = 0.001], the number of comorbidities > 2 (OR = 2.124, p = 0.014), and albumin (ALB) < 35 g/L (OR = 1.516, p = 0.043), etc. were significantly associated with the development of preoperative DVT in geriatric intertrochanteric fracture patients. Conclusions Although routine anticoagulant therapy was used to prevent the formation of DVT, the incidence of which was still high. Therefore, pre-operative ultrasound of both lower extremities was advised for pre-operatively, especially for patients with delayed surgery, hypoproteinemia, three or more comorbidities, and a d-dimer level > 1.59 mg/L.
引用
收藏
页码:351 / 359
页数:9
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