QUANTIFICATION OF LIVER FAT CONTENT WITH ULTRASOUND: A WFUMB POSITION PAPER

被引：110

作者：

Ferraioli, Giovanna ^{[1
]}

Berzigotti, Annalisa ^{[2
]}

Barr, Richard G. ^{[3
]}

Choi, Byung I. ^{[4
]}

Cui, Xin Wu ^{[5
]}

Dong, Yi ^{[6
]}

Gilja, Odd Helge ^{[7
,8
]}

Lee, Jae Young ^{[9
,10
,11
,12
,13
]}

Lee, Dong Ho ^{[14
]}

Moriyasu, Fuminori ^{[15
]}

Piscaglia, Fabio ^{[16
]}

Sugimoto, Katsutoshi ^{[17
]}

Wong, Grace Lai-Hung ^{[18
,19
]}

Wong, Vincent Wai-Sun ^{[20
]}

Dietrich, Christoph F. ^{[21
]}

机构：

[1] Univ Pavia, Med Sch, Dept Clin Surg Diagnost & Pediat Sci, Pavia, Italy

[2] Univ Bern, Univ Hosp Bern, Univ Clin Visceral Surg & Med, Hepatol Dept,Inselspital, Bern, Switzerland

[3] Northeastern Ohio Med Univ, Dept Radiol, Rootstown, OH USA

[4] Chung Ang Univ Hosp, Dept Radiol, Seoul, South Korea

[5] Huazhong Univ Sci & Technol, Tongji Hosp, Dept Med Ultrasound, Tongji Med Coll, Wuhan, Peoples R China

[6] Fudan Univ, Zhongshan Hosp, Dept Ultrasound, Shanghai, Peoples R China

[7] Haukeland Hosp, Natl Ctr Ultrasound Gastroenterol, Bergen, Norway

[8] Univ Bergen, Dept Clin Med, Bergen, Norway

[9] Sungkyunkwan Univ, Samsung Adv Inst Hlth Sci & Technol, Dept Hlth, Seoul, South Korea

[10] Sungkyunkwan Univ, Samsung Adv Inst Hlth Sci & Technol, Dept Sci, Seoul, South Korea

[11] Sungkyunkwan Univ, Samsung Adv Inst Hlth Sci & Technol, Dept Technol, Seoul, South Korea

[12] Sungkyunkwan Univ, Samsung Adv Inst Hlth Sci & Technol, Dept Med Device Management, Seoul, South Korea

[13] Sungkyunkwan Univ, Samsung Adv Inst Hlth Sci & Technol, Dept Res, Seoul, South Korea

[14] Seoul Natl Univ Hosp, Dept Radiol, Seoul, South Korea

[15] Int Univ Hlth & Welf, Sanno Hosp, Dept Gastroenterol & Hepatol, Tokyo, Japan

[16] Univ Bologna, Dept Med & Surg Sci, Unit Internal Med Hepatobiliary & Immunoallerg Di, S Orsola Malpighi Hosp, Bologna, Italy

[17] Tokyo Med Univ, Dept Gastroenterol & Hepatol, Tokyo, Japan

[18] Chinese Univ Hong Kong, Med Data Analyt Ctr, Hong Kong, Peoples R China

[19] Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Peoples R China

[20] Chinese Univ Hong Kong, Dept Med & Therapeut, Fac Med, Hong Kong, Peoples R China

[21] Kliniken Hirslanden Beau Site Salem & Permancence, Dept Allgemeine Innere Med DAIM, Bern, Switzerland

来源：

ULTRASOUND IN MEDICINE AND BIOLOGY | 2021年 / 47卷 / 10期

关键词：

Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Controlled attenuation parameter; Dispersion; Backscatter; Speed of sound; Attenuation coefficient; Quantitative ultrasound; CONTROLLED ATTENUATION PARAMETER; ACOUSTIC STRUCTURE QUANTIFICATION; METABOLIC SYNDROME INCREASES; CANCEROUS HUMAN-LIVER; CHRONIC HEPATITIS-C; TRANSIENT ELASTOGRAPHY; NONINVASIVE DIAGNOSIS; QUANTITATIVE ULTRASOUND; HEPATORENAL INDEX; CLINICAL-VALUE;

D O I：

10.1016/j.ultrasmedbio.2021.06.002

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

New ultrasound methods that can be used to quantitatively assess liver fat content have recently been developed. These quantitative ultrasound (QUS) methods are based on the analysis of radiofrequency echoes detected by the transducer, allowing calculation of parameters for quantifying the fat in the liver. In this position paper, after a section dedicated to the importance of quantifying liver steatosis in patients with non-alcoholic fatty liver disease and another section dedicated to the assessment of liver fat with magnetic resonance, the current clinical studies performed using QUS are summarized. These new methods include spectral-based techniques and techniques based on envelope statistics. The spectral-based techniques that have been used in clinical studies are those estimating the attenuation coefficient and those estimating the backscatter coefficient. Clinical studies that have used tools based on the envelope statistics of the backscattered ultrasound are those performed by using the acoustic structure quantification or other parameters derived from it, such as the normalized local variance, and that performed by estimating the speed of sound. Experts' opinions are reported. (E-mail: ChristophFrank. Dietrich@hirslanden.ch) (c) 2021 World Federation for Ultrasound in Medicine & Biology. All rights reserved.

引用

页码：2803 / 2820

页数：18

共 50 条

[41] Ultrasound evaluation of liver fibrosis: preliminary experience with acoustic structure quantification (ASQ) software [J].

Ricci, Paolo ;

Marigliano, Chiara ;

Cantisani, Vito ;

Porfiri, Andrea ;

Marcantonio, Andrea ;

Lodise, Pietro ;

D'Ambrosio, Ugo ;

Labbadia, Giancarlo ;

Maggini, Elena ;

Mancuso, Ester ;

Panzironi, Giovanna ;

Di Segni, Mattia ;

Furlan, Caterina ;

Masciangelo, Raffaele ;

Taliani, Gloria .

RADIOLOGIA MEDICA, 2013, 118 (06) :995-1010

[42] Quantification of Hepatic Steatosis by Ultrasound: Prospective Comparison With MRI Proton Density Fat Fraction as Reference Standard [J].

Dillman, Jonathan R. ;

Thapaliya, Samjhana ;

Tkach, Jean A. ;

Trout, Andrew T. .

AMERICAN JOURNAL OF ROENTGENOLOGY, 2022, 219 (05) :784-791

[43] Diagnosis of Nonalcoholic Fatty Liver Disease in Children and Adolescents: Position Paper of the ESPGHAN Hepatology Committee [J].

Vajro, Pietro ;

Lenta, Selvaggia ;

Socha, Piotr ;

Dhawan, Anil ;

McKiernan, Patrick ;

Baumann, Ulrich ;

Durmaz, Ozlem ;

Lacaille, Florence ;

McLin, Valerie ;

Nobili, Valerio .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2012, 54 (05) :700-713

[44] Liver Fat Droplet Dependency on Ultrasound Backscatter Coefficient in Nonalcoholic Fatty Liver [J].

Wu, Yashuo ;

Lopez, Leonardo ;

Andre, Michael P. ;

Loomba, Rohit ;

Sirlin, Claude B. ;

Valasek, Mark A. ;

Wallig, Matthew A. ;

O'Brien, William D., Jr. ;

Han, Aiguo .

PROCEEDINGS OF THE 2020 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), 2020,

[45] Ultrasound-based hepatic fat quantification: current status and future directions [J].

Seneviratne, N. ;

Fang, C. ;

Sidhu, P. S. .

CLINICAL RADIOLOGY, 2023, 78 (03) :187-200

[46] STEATO-SCORE: NON-INVASIVE QUANTITATIVE ASSESSMENT OF LIVER FAT BY ULTRASOUND IMAGING [J].

Di Lascio, Nicole ;

Avigo, Cinzia ;

Salvati, Antonio ;

Martini, Nicola ;

Ragucci, Monica ;

Monti, Serena ;

Prinster, Anna ;

Chiappino, Dante ;

Mancini, Marcello ;

D'Elia, Domenico ;

Ghiadoni, Lorenzo ;

Bonino, Ferruccio ;

Brunetto, Maurizia R. ;

Faita, Francesco .

ULTRASOUND IN MEDICINE AND BIOLOGY, 2018, 44 (08) :1585-1596

[47] Quantification of Liver Fat with Magnetic Resonance Imaging [J].

Reeder, Scott B. ;

Sirlin, Claude B. .

MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICA, 2010, 18 (03) :337-+

[48] Quantification of liver fat content with ultrasonographic attenuation measurement function: Correlation with unenhanced multidimensional computerized tomography [J].

Cerit, Mahinur ;

Sendur, Halit Nahit ;

Cindil, Emetullah ;

Erbas, Gonca ;

Yalcin, Mehmet Muhittin ;

Cerit, Ethem Turgay ;

Allahverdiyeva, Seriyye ;

Oktar, Suna Ozhan ;

Yucel, Cem .

CLINICAL IMAGING, 2020, 65 :85-93

[49] Diagnostic Performance of Ultrasound-Based Liver Fat Quantification With Reference to Magnetic Resonance Imaging Proton Density Fat Fraction and Histology [J].

Dag, Nurullah ;

Sarici, Baris ;

Igci, Gulnur ;

Yagin, Fatma Hilal ;

Yilmaz, Sezai ;

Kutlu, Ramazan .

JOURNAL OF CLINICAL ULTRASOUND, 2025, 53 (06) :1265-1271

[50] In vivo 3T spectroscopic quantification of liver fat content in nonalcoholic fatty liver disease: Correlation with biochemical method and morphometry [J].

Roldan-Valadez, Ernesto ;

Favila, Rafael ;

Martinez-Lopez, Manuel ;

Uribe, Misael ;

Rios, Camilo ;

Mendez-Sanchez, Nahum .

JOURNAL OF HEPATOLOGY, 2010, 53 (04) :732-737

← 1 2 3 4 5 →