Separation of liquid domains in model membranes induced with high hydrostatic pressure

被引:24
作者
McCarthy, Nicola L. C. [1 ]
Ces, Oscar [1 ]
Law, Robert V. [1 ]
Seddon, John M. [1 ]
Brooks, Nicholas J. [1 ]
机构
[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AZ, England
基金
英国工程与自然科学研究理事会;
关键词
LIPID RAFTS; MIXTURES; SPECTROSCOPY; VESICLES; PHASES;
D O I
10.1039/c5cc02134k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We have imaged the formation of membrane microdomains immediately after their induction using a novel technology platform coupling high hydrostatic pressure to fluorescence microscopy. After formation, the ordered domains are small and highly dynamic. This will enhance links between model lipid assemblies and dynamic processes in cellular membranes.
引用
收藏
页码:8675 / 8678
页数:4
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