Cdc42/Rho GTPases in fungi: variations on a common theme

被引：58
作者：
Harris, Steven D. [1 ,2 ]
机构：
[1] Univ Nebraska, Dept Plant Pathol, Lincoln, NE 68688 USA
[2] Univ Nebraska, Ctr Plant Sci Innovat, Lincoln, NE 68688 USA
来源：
MOLECULAR MICROBIOLOGY | 2011年 / 79卷 / 05期
基金：
美国国家科学基金会;
关键词：
CELL POLARITY; PENICILLIUM-MARNEFFEI; SEPTUM FORMATION; HYPHAL GROWTH; RAS; MORPHOGENESIS; HOMOLOG; RAC1; ACTIVATION; VIRULENCE;
D O I：
10.1111/j.1365-2958.2010.07525.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
P>Cdc42/Rho GTPases are universally important regulators of cellular morphogenesis. Whereas their functions are well characterized in budding yeast, they are only beginning to be understood in filamentous fungi. The recent systematic analysis of Cdc42, Rac1 and Rho function in Aspergillus niger provides the first global perspective on their respective roles in hyphal morphogenesis. Surprisingly, the partitioning of these roles between Cdc42 and Rac1 seems to vary even among related fungi. These observations highlight the variable use of a common signalling module in filamentous fungi.
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收藏
页码：1123 / 1127
页数：5
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