Chronic renal failure in Iranian children

被引：54

作者：

Madani, K

Otoukesh, H

Rastegar, A

Van Why, S

机构：

[1] Yale Univ, Sch Med, Dept Pediat, New Haven, CT 06520 USA

[2] Yale Univ, Sch Med, Dept Internal Med, New Haven, CT 06510 USA

[3] Iranian Univ Med Sci, Ali Asghar Childrens Hosp, Dept Nephrol, Teheran, Iran

来源：

PEDIATRIC NEPHROLOGY | 2001年 / 16卷 / 02期

关键词：

chronic renal failure; etiology; Iranian children;

D O I：

10.1007/s004670000522

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

We investigated chronic renal failure (CRF) in 166 Iranian children (95 boys and 71 girls) from July 1991 to June 1999. The mean age at onset of CRF was 7.9+/-4.5 years. The most common cause of CRF was congenital urological malformations (78 cases). The secund most common cause of CRF was hereditary nephropathy (21%). Glomerular diseases accounted for only 10% of children who later went on to develop renal failure. High rates of cystinosis and primary hyperoxaluria were seen, and these elevated rates could be due to a high prevalence of parental consanguinity. Eighty-six patients required renal replacement therapy, of whom the majority underwent hemodialysis. The prevalence of primary reflux as a cause of CRF was high compared with reports from western countries. Earlier diagnosis and manage ment of urinary tract infections in this group could reduce the prevalence of reflux as a cause of CRF in this population.

引用

页码：140 / 144

页数：5