Impact of prolonged cardiopulmonary bypass and operative exposure time on the incidence of surgical site infections in patients undergoing open heart surgery: Single center case series

Introduction: Surgical site infections (SSIs) are either superficial or deep and may involve the organ. The reported incidence of SSIs in coronary artery bypass grafting (CABG) surgery ranges from 0.3% to 8%. While the incidence of superficial wound infection is 3-5% and deep sternal wound infection is 0,5-5%. Objectives of the current study is to determine the relation of prolonged CPB time and rate of SSI in patients underwent open heart surgery. Methods: prospective observational study included all patients underwent open heart surgery in our center, The patients followed-up within 2-3 month of their periodical visits. The data collection was performed from January 1st 2018 to January 1st 2019. Relevant data were entered into a database created using Microsoft Access 2007 program & then analyzed via specific queries. Results: The mean age of the patients were 55.32 (SD: 22.82 years) ranged from 30 to 81 years. Most of the patients were male 69.7%). The mean exposure time of the operation and cardiopulmonary bypass time (CBPT) were 4.30 (SD: 1.0 h) and 140.38 (SD: 56.03 min), respectively. The mean duration of the patients in ICU was 21.34 (SD: 7.58 h).In this study, 17 patients (4.5%) developed SSIs. The incidence of prolonged surgery was 37.8%. The study showed that those patients developed infection had a greater operation exposure time (4.88 vs. 4.27hrs.), and CBPT (161.59 vs. 56.53 min). Conclusion: The operation exposure and CBP times were directly related to the occurrence of surgical site infection. (c) 2019 The Authors. Published by Elsevier Ltd on behalf of Surgical Associates Ltd.