β-Sultams -: A novel class of serine protease inhibitors

被引：37

作者：

Beardsell, M

Hinchliffe, PS

Wood, JM

Wilmouth, RC

Schofield, CJ

Page, MI ^{[1
]}

机构：

[1] Univ Huddersfield, Dept Chem & Biol Sci, Huddersfield HD1 3DH, W Yorkshire, England

[2] Oxford Ctr Mol Sci, Oxford OX1 3QY, England

[3] Dyson Perrins Lab, Oxford OX1 3QY, England

来源：

CHEMICAL COMMUNICATIONS | 2001年 / 05期

关键词：

D O I：

10.1039/b100294p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

N-Benzoyl beta -sultam is an irreversible inactivator of elastase by sulfonation of the active site serine.

引用

页码：497 / 498

页数：2

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