Modulation of Central Synapses by Astrocyte-Released ATP and Postsynaptic P2X Receptors

被引：64
作者：
Boue-Grabot, Eric [1 ,2 ]
Pankratov, Yuriy [3 ,4 ]
机构：
[1] Univ Bordeaux, UMR 5293, Inst Malad Neurodegenerat, F-33000 Bordeaux, France
[2] CNRS, UMR 5293, Inst Malad Neurodegenerat, F-33000 Bordeaux, France
[3] Univ Warwick, Sch Life Sci, Coventry, W Midlands, England
[4] Immanuel Kant Balt Fed Univ, Sch Life Sci, Kaliningrad, Russia
来源：
NEURAL PLASTICITY | 2017年 / 2017卷
关键词：
GAMMA-AMINOBUTYRIC-ACID; SYNAPTIC-TRANSMISSION; CROSS-TALK; NERVOUS-SYSTEM; CORTICAL ASTROCYTES; GLUTAMATE RELEASE; EXTRACELLULAR ATP; PLASMA-MEMBRANE; A-RECEPTORS; NEURONS;
D O I：
10.1155/2017/9454275
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Communication between neuronal and glial cells is important for neural plasticity. P2X receptors are ATP-gated cation channels widely expressed in the brain where they mediate action of extracellular ATP released by neurons and/or glia. Recent data show that postsynaptic P2X receptors underlie slow neuromodulatory actions rather than fast synaptic transmission at brain synapses. Here, we review these findings with a particular focus on the release of ATP by astrocytes and the diversity of postsynaptic P2X-mediated modulation of synaptic strength and plasticity in the CNS.
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页数：11
相关论文
共 105 条
[21]   The Cellular Phase of Alzheimer's Disease [J].
De Strooper, Bart ;
Karran, Eric .
CELL, 2016, 164 (04) :603-615
[22]   α1-Adrenergic receptors mediate coordinated Ca2+ signaling of cortical astrocytes in awake, behaving mice [J].
Ding, Fengfei ;
O'Donnell, John ;
Thrane, Alexander S. ;
Zeppenfeld, Douglas ;
Kang, Hongyi ;
Xie, Lulu ;
Wang, Fushun ;
Nedergaard, Maiken .
CELL CALCIUM, 2013, 54 (06) :387-394
[23]   ATP RECEPTOR-MEDIATED SYNAPTIC CURRENTS IN THE CENTRAL-NERVOUS-SYSTEM [J].
EDWARDS, FA ;
GIBB, AJ ;
COLQUHOUN, D .
NATURE, 1992, 359 (6391) :144-147
[24]   Properties of ATP receptor-mediated synaptic transmission in the rat medial habenula [J].
Edwards, FA ;
Robertson, SJ ;
Gibb, AJ .
NEUROPHARMACOLOGY, 1997, 36 (09) :1253-1268
[25]   A New Mechanism of Receptor Targeting by Interaction between Two Classes of Ligand-Gated Ion Channels [J].
Emerit, Michel Boris ;
Baranowski, Camille ;
Diaz, Jorge ;
Martinez, Audrey ;
Areias, Julie ;
Alterio, Jeanine ;
Masson, Justine ;
Boue-Grabot, Eric ;
Darmon, Michele .
JOURNAL OF NEUROSCIENCE, 2016, 36 (05) :1456-1470
[26]   Purinergic signalling in neuron-glia interactions [J].
Fields, R. Douglas ;
Burnstock, Geoffrey .
NATURE REVIEWS NEUROSCIENCE, 2006, 7 (06) :423-436
[27]   ATP: an extracellular signaling molecule between neurons and glia [J].
Fields, RD ;
Stevens, B .
TRENDS IN NEUROSCIENCES, 2000, 23 (12) :625-633
[28]   FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels [J].
Garre, Juan M. ;
Retamal, Mauricio A. ;
Cassina, Patricia ;
Barbeito, Luis ;
Bukauskas, Feliksas F. ;
Saez, Juan C. ;
Bennett, Michael V. L. ;
Abudara, Veronica .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2010, 107 (52) :22659-22664
[29]   Microglia-derived purines modulate mossy fibre synaptic transmission and plasticity through P2X4 and A1 receptors [J].
George, Jimmy ;
Cunha, Rodrigo A. ;
Mulle, Christophe ;
Amedee, Thierry .
EUROPEAN JOURNAL OF NEUROSCIENCE, 2016, 43 (10) :1366-1378
[30]  
Gómez-Villafuertes R, 2001, J NEUROCHEM, V77, P84, DOI 10.1046/j.1471-4159.2001.t01-1-00228.x
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