Effects of D-amphetamine on short- and long-term memory in spontaneously hypertensive, Wistar-Kyoto and Sprague-Dawley rats

被引:21
|
作者
Meneses, A. [1 ]
Ponce-Lopez, T. [1 ]
Tellez, R. [1 ]
Gonzalez, R. [1 ]
Castillo, C. [2 ]
Gasbarri, A. [3 ]
机构
[1] CINVESTAV, Dept Pharmacol, Mexico City 14330, DF, Mexico
[2] Escuela Super Med IPN, Mexico City, DF, Mexico
[3] Univ Aquila, Dept Biomed Sci & Technol, Fac Sci Educ, I-67100 Laquila, Italy
关键词
Memory; Attention; Hyperactivity; Autoshaping; D-Amphetamine; ADHD; SHR; STM; LTM; WKY; Sprague-Dawley; Rats; DEFICIT HYPERACTIVITY DISORDER; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; WORKING-MEMORY; PREFRONTAL CORTEX; ANIMAL-MODEL; SEROTONIN/DOPAMINE INTERACTION; 5-HT7; RECEPTORS; ADHD; DRUGS; STIMULATION;
D O I
10.1016/j.bbr.2010.08.035
中图分类号
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要
Diverse studies indicate that the attention deficit hyperactivity disorder (ADHD) is associated with alterations in encoding processes, including working or short-term memory. Some ADHD dysfunctional domains are reflected in the spontaneously hypertensive rat (SHR). Here SHR-saline group showed significantly poor STM and LTM relative to SD and WKY saline rats. SD and WKY rats treated with D-amphetamine displayed better STM and LTM, compared to SD-vehicle, WKY-vehicle or SHR-D-amphetamine groups. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:472 / 476
页数:5
相关论文
共 50 条