Acute reactive arthritis after intravesical instillation of bacillus Calmette-Guerin. Two case reports and literature review

被引：9
作者：
Miranda, S. [1 ]
Vernet, M. [2 ]
Heron, F. [1 ]
Vittecoq, O. [2 ]
Levesque, H. [1 ]
Marie, I. [1 ]
机构：
[1] CHU Rouen Biosguillaume, Dept Med Interne, F-76031 Rouen, France
[2] CHU Rouen Biosguillaume, Serv Rhumatol, F-76031 Rouen, France
来源：
REVUE DE MEDECINE INTERNE | 2010年 / 31卷 / 08期
关键词：
Bladder cancer; BCG-therapy; Adverse effects; Articular involvement; Reactive arthritis; ADJUVANT MYCOBACTERIAL TREATMENT; BCG-THERAPY; BLADDER-CANCER; REITERS-SYNDROME; ACUTE POLYARTHRITIS; CARCINOMA; IMMUNOTHERAPY; COMPLICATIONS; ARTHROPATHY; SECONDARY;
D O I：
10.1016/j.revmed.2010.01.010
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Introduction. - Intravesical bacillus Calmette-Guerin (BCG) therapy-associated articular complications are uncommon, occurring in only 0.5 to 1% of the patients. Observations. - We report two patients who were given intravesical BCG therapy for superficial bladder cancer. Both patients developed polyarthritis and fever related to intravesical BCG instillation. The outcome of articular manifestations was favorable after administration of nonsteroidal anti-inflammatory therapy. Conclusion. - Intravesical BCG therapy-associated articular complications should not be overlooked, as they may result in high morbidity. Nevertheless, the diagnosis of intravesical BCG therapy-related reactive arthritis should be discussed after excluding infectious arthritis due to Mycobacterium bovis. Therefore, joint fluid microbiological tests (cultures, PCR) are required in the patients receiving intravesical BCG who develop arthritis. (C) 2010 Societe nationale francaise de medecine interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：558 / 561
页数：4
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