Medical Treatment of Hypertension in Patients with Heart Failure with Preserved Ejection Fraction

被引:2
作者
Kiel, Richard G. [1 ]
Deedwania, Prakash [1 ]
机构
[1] UCSF Fresno Med Educ Program, Vet Affairs Cent Calif Hlth Care Syst, Fresno, CA 93703 USA
关键词
Hypertension; Heart failure with preserved ejection fraction; HF-PEF; Diastolic heart failure; Medical treatment; LEFT-VENTRICULAR HYPERTROPHY; LIPID-LOWERING TREATMENT; END-POINT REDUCTION; LOSARTAN INTERVENTION; RANDOMIZED-TRIAL; REGRESSION; MORTALITY; VERAPAMIL; TERM;
D O I
10.1007/s11886-013-0428-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Heart failure with preserved ejection fraction (HFPEF) has become an increasingly common problem, accounting for as many as half of all diagnoses of heart failure. Hypertension has been shown to be a major risk factor for the development of HPEF, and the treatment of hypertension is key to both preventing the development of HFPEF as well as mitigating its impact on our health care system. While numerous studies have looked at using various classes of antihypertensive medications to treat HFPEF, there are still no well validated treatment strategies which have shown a significant mortality benefit. As a result, when choosing an antihypertensive medication to treat or prevent HFPEF, it is important to tailor the choice of antihypertensive medication to an individual patient's specific symptoms and comorbidities.
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