Cutaneous cytotoxic T-cell lymphoma

被引：0

作者：

Weinstabl, A. ^{[1
]}

Megahed, M. ^{[1
]}

Ruetten, A. ^{[2
]}

Ruebben, A. ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Klin Dermatol & Allergol, D-52074 Aachen, Germany

[2] Dermatopathol Friedrichshafen, Bodensee, Germany

来源：

HAUTARZT | 2011年 / 62卷 / 05期

关键词：

Cutaneous cytotoxic T-cell lymphoma; Atypical lymphocytes; CD56+; Methotrexate; Bexarotene;

D O I：

10.1007/s00105-011-2165-2

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Cutaneous cytotoxic T-cell lymphoma is a rare variant of cutaneous T-cell lymphoma, which shows immunoreactivity for CD56+. We report on an 83-year old woman with numerous skin infiltrates and nodules mainly on her face and trunk. Histopathologic criteria lead to the diagnosis of cutaneous cytotoxic T-cell lymphoma. Bexarotene was not tolerated because of cardiac insufficiency, but treatment with methotrexate (7.5 mg once weekly) led to prompt regression of all lesions.

引用

页码：329 / +

页数：3

共 9 条

[1] Cutaneous Lymphomas: from Morphology to Chip Technology [J].

Cerroni, L. ;

Wiesner, T. .

ACTAS DERMO-SIFILIOGRAFICAS, 2009, 100 :3-17

[2] Therapy of cutaneous lymphoma -: Current practice and future developments [J].

Dummer, R ;

Kempf, W ;

Schmid, MH ;

Häffner, A ;

Burg, G .

ONKOLOGIE, 2003, 26 (04) :366-372

[3]

Dummer R, 2005, INTERDISZIPLINARE LE, P83

[4] Novel Therapies for Cutaneous T-Cell Lymphomas [J].

Horwitz, Steven M. .

CLINICAL LYMPHOMA & MYELOMA, 2008, 8 :S187-S192

[5] Management of refractory early-stage cutaneous T-cell lymphoma [J].

Huber, Margit A. ;

Staib, Gyde ;

Pehamberger, Hubert ;

Scharffetter-Kochanek, Karin .

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2006, 7 (03) :155-169

[6]

Hymes Kenneth B, 2007, Oncology (Williston Park), V21, P18

[7] Current and Emerging Treatment Strategies for Cutaneous T-cell Lymphoma [J].

Lansigan, Frederick ;

Foss, Francine M. .

DRUGS, 2010, 70 (03) :273-286

[8] Treatment of Cutaneous Lymphomas: Today and Tomorrow [J].

Mestel, D. S. ;

Beyer, M. ;

Steinhoff, M. ;

Sterry, W. .

ACTAS DERMO-SIFILIOGRAFICAS, 2009, 100 :18-32

[9] Classification of cutaneous T-cell lymphoma: from Alibert to WHO-EORTC [J].

Willemze, R ;

Meijer, CJLM .

JOURNAL OF CUTANEOUS PATHOLOGY, 2006, 33 :18-26

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