10TH CONFERENCE ON INTERDISCIPLINARY PROBLEMS IN ENVIRONMENTAL PROTECTION AND ENGINEERING EKO-DOK 2018
|
2018年
/
44卷
关键词:
ASSESSING CHEMICAL TOXICITY;
VIBRIO-FISCHERI;
GENOTOXICITY;
BIOASSAYS;
EXPOSURE;
D O I:
10.1051/e3sconf/20184400066
中图分类号:
X [环境科学、安全科学];
学科分类号:
08 ;
0830 ;
摘要:
The ecotoxicity assessment of new substances is crucial for their considered launch on the market. Due to various properties of chemical compounds, however, the application of biotests can be challenging. In the case of insoluble compounds, a proper, non-toxic solvent must be applied. The presented preliminary results demonstrate the extremely high ecotoxicity of camphor and camphor oxime, assessed by means of the Microtox system. A 81.9% Basic Test with 14 dilutions was applied. The ecotoxicity of a solvent (i.e. DMSO) was also assessed. The initial concentration of substances was 5%. EC50 values reached 0.00023% and 0.00007% for camphor and camphor oxime, respectively, after 15 min. of incubation of the samples with bioluminescent bacteria. The ecotoxicity of the solvent remained negligible. Due to the extremely high ecotoxicity values of the tested substances, another range of concentrations needs to be applied in future tests to confirm the results.
机构:
Inst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, CroatiaInst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia
Gajski, Goran
Ladeira, Carina
论文数: 0引用数: 0
h-index: 0
机构:
Inst Politecn Lisboa, Escola Super Tecnol Saude Lisboa, Grp Invest Ambiente & Saude, Lisbon, Portugal
Inst Politecn Lisboa, Escola Super Tecnol Saude Lisboa, Grp Invest Genet & Metab, Lisbon, PortugalInst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia
Ladeira, Carina
Geric, Marko
论文数: 0引用数: 0
h-index: 0
机构:
Inst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, CroatiaInst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia
Geric, Marko
Garaj-Vrhovac, Vera
论文数: 0引用数: 0
h-index: 0
机构:
Inst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, CroatiaInst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia
Garaj-Vrhovac, Vera
Viegas, Susana
论文数: 0引用数: 0
h-index: 0
机构:
Inst Politecn Lisboa, Escola Super Tecnol Saude Lisboa, Grp Invest Ambiente & Saude, Lisbon, Portugal
Univ NOVA Lisboa, Ctr Invest Saude Publ, Escola Nacl Saude Publ, Lisbon, PortugalInst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia
机构:
Inst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, CroatiaInst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia
Gajski, Goran
Ladeira, Carina
论文数: 0引用数: 0
h-index: 0
机构:
Inst Politecn Lisboa, Escola Super Tecnol Saude Lisboa, Grp Invest Ambiente & Saude, Lisbon, Portugal
Inst Politecn Lisboa, Escola Super Tecnol Saude Lisboa, Grp Invest Genet & Metab, Lisbon, PortugalInst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia
Ladeira, Carina
Geric, Marko
论文数: 0引用数: 0
h-index: 0
机构:
Inst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, CroatiaInst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia
Geric, Marko
Garaj-Vrhovac, Vera
论文数: 0引用数: 0
h-index: 0
机构:
Inst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, CroatiaInst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia
Garaj-Vrhovac, Vera
Viegas, Susana
论文数: 0引用数: 0
h-index: 0
机构:
Inst Politecn Lisboa, Escola Super Tecnol Saude Lisboa, Grp Invest Ambiente & Saude, Lisbon, Portugal
Univ NOVA Lisboa, Ctr Invest Saude Publ, Escola Nacl Saude Publ, Lisbon, PortugalInst Med Res & Occupat Hlth, Mutagenesis Unit, Zagreb, Croatia