A highly selective and sensitive photoinduced electron transfer (PET) based HOCl fluorescent probe in water and its endogenous imaging in living cells

被引：100

作者：

Liang, Lijuan ^{[1
]}

Liu, Chang ^{[1
,2
]}

Jiao, Xiaojie ^{[2
]}

Zhao, Liancheng ^{[1
]}

Zeng, Xianshun ^{[2
]}

机构：

[1] Harbin Inst Technol, Sch Mat Sci & Engn, Harbin 150001, Peoples R China

[2] Tianjin Univ Technol, Tianjin Key Lab Photoelect Mat & Devices, Tianjin 300384, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 51期

关键词：

HYPOCHLOROUS ACID; LIVE CELLS; DUAL-EMISSION; CANCER-CELLS; REDOX CYCLE; SE-BODIPY; HCLO; MITOCHONDRIA; DNA; MYELOPEROXIDASE;

D O I：

10.1039/c6cc02603f

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A probe based on the phenothiazine-acridine orange conjugate (Ptz-AO) has been designed and synthesized for the sensitive and selective detection of HOCl. Ptz-AO has excellent properties, including pH-independence of fluorescence, high resistance to photobleaching, and response in real time. The value of Ptz-AO was confirmed by exogenous, endogenous and the real-time imaging of HOCl in vitro using a fluorescence microscope.

引用

页码：7982 / 7985

页数：4

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