An efficient and rapid Mn(III) complex catalyzed synthesis of polyhydropyridine derivatives via Hantzsch four component condensation

A facile and an efficient one-pot synthesis of polyhydroquinoline derivatives in high yields using N,N'-bis (benzoylacetone) ethylenediamine manganese (III) chloride as an environmentally friendly mild Lewis acid catalyst with high catalytic activity and reusability via the Hantzsch reaction in short reaction time was reported. The reaction proceeded to completion within 5-25 min in 90-97% yield. All of the obtained compounds were obtained in high purity without any use of more purification and characterized by physical and spectroscopic data. (C) 2010 King Saud University. Production and hosting by Elsevier B. V. All rights reserved.