Melanoma: Epidemiology, Diagnosis, Treatment, and Outcomes

被引：54
作者：
Tuong, William [1 ]
Cheng, Lily S. [1 ]
Armstrong, April W. [1 ]
机构：
[1] Univ Calif Davis, Univ Calif Davis Hlth Syst, Dermatol Clin Res Unit, Teledermatol Program,Dept Dermatol,Sch Med, Sacramento, CA 95816 USA
来源：
DERMATOLOGIC CLINICS | 2012年 / 30卷 / 01期
关键词：
Melanoma; Epidemiology; Cause; Prevention; Treatment; Prognosis; CUTANEOUS MALIGNANT-MELANOMA; HIGH-RISK MELANOMA; SKIN-CANCER; ULTRAVIOLET-RADIATION; GERMLINE MUTATION; INTERFERON-ALPHA; SELF-EXAMINATION; LENTIGO-MALIGNA; FAMILY-HISTORY; MOHS SURGERY;
D O I：
10.1016/j.det.2011.08.006
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Melanoma is a skin cancer that arises from the malignant transformation of melanocytes. Although it is typically considered a pigmented lesion, the clinical presentation of melanoma can vary greatly. With increased efforts in screening and detection of early-stage melanoma, researchers and clinicians hope to improve clinical outcomes for patients with melanoma. Novel immunotherapies directed at specific molecular targets in the pathogenesis of melanoma usher in a new era of treatment of advanced melanoma.
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收藏
页码：113 / +
页数：13
相关论文
共 110 条
[81]  
Ng JC, 2010, ARCH DERMATOL, V146, P234, DOI 10.1001/archdermatol.2010.14
[82]   Estimating the Attributable Fraction for Cancer: A Meta-analysis of Nevi and Melanoma [J].
Olsen, Catherine M. ;
Carroll, Heidi J. ;
Whiteman, David C. .
CANCER PREVENTION RESEARCH, 2010, 3 (02) :233-245
[83]   METASTATIC PATTERN OF MALIGNANT-MELANOMA - STUDY OF 216 AUTOPSY CASES [J].
PATEL, JK ;
DIDOLKAR, MS ;
PICKREN, JW ;
MOORE, RH .
AMERICAN JOURNAL OF SURGERY, 1978, 135 (06) :807-810
[84]   Multimethod imaging, staging, and spectrum of manifestations of metastatic melanoma [J].
Patnana, M. ;
Bronstein, Y. ;
Szklaruk, J. ;
Bedi, D. G. ;
Hwu, W-J ;
Gershenwald, J. E. ;
Prieto, V. G. ;
Ng, C. S. .
CLINICAL RADIOLOGY, 2011, 66 (03) :224-236
[85]   Who should have Mohs micrographic surgery? [J].
Perkins, William .
CURRENT OPINION IN OTOLARYNGOLOGY & HEAD AND NECK SURGERY, 2010, 18 (04) :283-289
[86]   Timing of excessive ultraviolet radiation and melanoma:: epidemiology does not support the existence of a critical period of high susceptibility to solar ultraviolet radiation-induced melanoma [J].
Pfahlberg, A ;
Kölmel, KF ;
Gefeller, O .
BRITISH JOURNAL OF DERMATOLOGY, 2001, 144 (03) :471-475
[87]   Sentinel Lymph Node Biopsy for Melanoma: Indications and Rationale [J].
Phan, Giao Q. ;
Messina, Jane L. ;
Sondak, Vernon K. ;
Zager, Jonathan S. .
CANCER CONTROL, 2009, 16 (03) :234-239
[88]   Melanoma genetics: a review of genetic factors and clinical phenotypes in familial melanoma [J].
Pho, L ;
Grossman, D ;
Leachman, SA .
CURRENT OPINION IN ONCOLOGY, 2006, 18 (02) :173-179
[89]   High frequency of BRAF mutations in nevi [J].
Pollock, PM ;
Harper, UL ;
Hansen, KS ;
Yudt, LM ;
Stark, M ;
Robbins, CM ;
Moses, TY ;
Hostetter, G ;
Wagner, U ;
Kakareka, J ;
Salem, G ;
Pohida, T ;
Heenan, P ;
Duray, P ;
Kallioniemi, O ;
Hayward, NK ;
Trent, JM ;
Meltzer, PS .
NATURE GENETICS, 2003, 33 (01) :19-20
[90]   Cutaneous malignant melanoma: Classification and clinical diagnosis [J].
Porras, BH ;
Cockerell, CJ .
SEMINARS IN CUTANEOUS MEDICINE AND SURGERY, 1997, 16 (02) :88-96
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