Melanoma: Epidemiology, Diagnosis, Treatment, and Outcomes

被引:57
作者
Tuong, William [1 ]
Cheng, Lily S. [1 ]
Armstrong, April W. [1 ]
机构
[1] Univ Calif Davis, Univ Calif Davis Hlth Syst, Dermatol Clin Res Unit, Teledermatol Program,Dept Dermatol,Sch Med, Sacramento, CA 95816 USA
关键词
Melanoma; Epidemiology; Cause; Prevention; Treatment; Prognosis; CUTANEOUS MALIGNANT-MELANOMA; HIGH-RISK MELANOMA; SKIN-CANCER; ULTRAVIOLET-RADIATION; GERMLINE MUTATION; INTERFERON-ALPHA; SELF-EXAMINATION; LENTIGO-MALIGNA; FAMILY-HISTORY; MOHS SURGERY;
D O I
10.1016/j.det.2011.08.006
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Melanoma is a skin cancer that arises from the malignant transformation of melanocytes. Although it is typically considered a pigmented lesion, the clinical presentation of melanoma can vary greatly. With increased efforts in screening and detection of early-stage melanoma, researchers and clinicians hope to improve clinical outcomes for patients with melanoma. Novel immunotherapies directed at specific molecular targets in the pathogenesis of melanoma usher in a new era of treatment of advanced melanoma.
引用
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页码:113 / +
页数:13
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