Genome editing and beyond: what does it mean for the future of plant breeding?

被引:29
作者
Tien Van Vu [1 ,2 ]
Das, Swati [1 ]
Hensel, Goetz [3 ,4 ]
Kim, Jae-Yean [1 ,5 ]
机构
[1] Gyeongsang Natl Univ, Plant Mol Biol & Biotechnol Res Ctr, Div Appl Life Sci, BK21 Four Program, Jinju 660701, South Korea
[2] Agr Genet Inst, Natl Key Lab Plant Cell Biotechnol, Km 02,Pham Van Dong Rd,Co Nhue 1, Hanoi 11917, Vietnam
[3] Heinrich Heine Univ, Ctr Plant Genome Engn, Inst Plant Biochem, Univ Str 1, D-40225 Dusseldorf, Germany
[4] Palacky Univ Olomouc, Ctr Reg Hana Biotechnol & Agr Res, Czech Adv Technol & Res Inst, Olomouc 78371, Czech Republic
[5] Gyeongsang Natl Univ, Div Life Sci, 501 Jinju Daero, Jinju 52828, South Korea
基金
新加坡国家研究基金会;
关键词
Genome engineering; New plant breeding techniques; CRISPR-Cas; Crop breeding; Biotechnology regulation; STRAND BREAK REPAIR; TARGETED MUTAGENESIS; CROP IMPROVEMENT; GUIDE RNA; NICOTIANA-BENTHAMIANA; GENE; DNA; ARABIDOPSIS; CRISPR; RESISTANCE;
D O I
10.1007/s00425-022-03906-2
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Main conclusion Genome editing offers revolutionized solutions for plant breeding to sustain food production to feed the world by 2050. Therefore, genome-edited products are increasingly recognized via more relaxed legislation and community adoption. The world population and food production are disproportionally growing in a manner that would have never matched each other under the current agricultural practices. The emerging crisis is more evident with the subtle changes in climate and the running-off of natural genetic resources that could be easily used in breeding in conventional ways. Under these circumstances, affordable CRISPR-Cas-based gene-editing technologies have brought hope and charged the old plant breeding machine with the most energetic and powerful fuel to address the challenges involved in feeding the world. What makes CRISPR-Cas the most powerful gene-editing technology? What are the differences between it and the other genetic engineering/breeding techniques? Would its products be labeled as "conventional" or "GMO"? There are so many questions to be answered, or that cannot be answered within the limitations of our current understanding. Therefore, we would like to discuss and answer some of the mentioned questions regarding recent progress in technology development. We hope this review will offer another view on the role of CRISPR-Cas technology in future of plant breeding for food production and beyond.
引用
收藏
页数:16
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