The Complexity of SARS-CoV-2 Infection and the COVID-19 Pandemic

被引：23

作者：

da Silva Torres, Maria Karoliny ^{[1
,2
]}

Bichara, Carlos David Araujo ^{[1
,2
]}

de Almeida, Maria de Nazare do Socorro ^{[2
,3
]}

Vallinoto, Mariana Cayres ^{[1
,4
]}

Queiroz, Maria Alice Freitas ^{[1
,2
]}

Vallinoto, Izaura Maria Vieira Cayres ^{[1
]}

dos Santos, Eduardo Jose Melo ^{[2
,3
]}

de Carvalho, Carlos Alberto Marques ^{[5
]}

Vallinoto, Antonio Carlos R. ^{[1
,2
]}

机构：

[1] Fed Univ Para, Inst Biol Sci, Lab Virol, Belem, Para, Brazil

[2] Fed Univ Para, Grad Program Biol Infect & Parasit Agents, Belem, Para, Brazil

[3] Fed Univ Para, Inst Biol Sci, Lab Complex Dis, Belem, Para, Brazil

[4] Univ Ctr State Para, Belem, Para, Brazil

[5] State Univ Para, Dept Pathol, Ctr Biol & Hlth Sci, Belem, Para, Brazil

来源：

FRONTIERS IN MICROBIOLOGY | 2022年 / 13卷

关键词：

SARS-CoV-2; COVID-19; coronavirus; pandemic; infection; RESPIRATORY-SYNDROME-CORONAVIRUS; RECEPTOR-BINDING DOMAIN; VIRAL-INFECTIONS; SPIKE PROTEIN; SARS; ACE2; POLYMORPHISMS; ENTRY; LOPINAVIR/RITONAVIR; SUSCEPTIBILITY;

D O I：

10.3389/fmicb.2022.789882

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) led to the death of millions of people worldwide and thousands more infected individuals developed sequelae due to the disease of the new coronavirus of 2019 (COVID-19). The development of several studies has contributed to the knowledge about the evolution of SARS-CoV2 infection and the disease to more severe forms. Despite this information being debated in the scientific literature, many mechanisms still need to be better understood in order to control the spread of the virus and treat clinical cases of COVID-19. In this article, we carried out an extensive literature review in order to bring together, in a single article, the biological, social, genetic, diagnostic, therapeutic, immunization, and even socioeconomic aspects that impact the SAR-CoV-2 pandemic. This information gathered in this article will enable a broad and consistent reading of the main aspects related to the current pandemic.

引用

页数：18

共 232 条

[1] Exploring the Binding Mechanism of PF-07321332 SARS-CoV-2 Protease Inhibitor through Molecular Dynamics and Binding Free Energy Simulations [J].

Ahmad, Bilal ;

Batool, Maria ;

ul Ain, Qurat ;

Kim, Moon Suk ;

Choi, Sangdun .

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (17)

[2] HLA and AB0 Polymorphisms May Influence SARS-CoV-2 Infection and COVID-19 Severity [J].

Amoroso, Antonio ;

Magistroni, Paola ;

Vespasiano, Francesca ;

Bella, Antonino ;

Bellino, Stefania ;

Puoti, Francesca ;

Alizzi, Silvia ;

Vaisitti, Tiziana ;

Boros, Stefano ;

Grossi, Paolo Antonio ;

Trapani, Silvia ;

Lombardini, Letizia ;

Pezzotti, Patrizio ;

Deaglio, Silvia ;

Brusaferro, Silvio ;

Cardillo, Massimo .

TRANSPLANTATION, 2021, 105 (01) :193-200

[3]

Amraei R., 2020, CD209L CD209 ARE REC, DOI [10.1101/2020.06.22.165803, DOI 10.1101/2020.06.22.165803]

[4]

Andolfo I., 2020, SSRN ELECT J, V24, DOI [10.1101/2020.12.18.20248470, DOI 10.1101/2020.12.18.20248470]

[5] Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double-Membrane Vesicles [J].

Angelini, Megan M. ;

Akhlaghpour, Marzieh ;

Neuman, Benjamin W. ;

Buchmeier, Michael J. .

MBIO, 2013, 4 (04)

[6] Association of HLA-DRB1*09:01 with severe COVID-19 [J].

Anzurez, Alitzel ;

Naka, Izumi ;

Miki, Shoji ;

Nakayama-Hosoya, Kaori ;

Isshiki, Mariko ;

Watanabe, Yusuke ;

Nakamura-Hoshi, Midori ;

Seki, Sayuri ;

Matsumura, Takayuki ;

Takano, Tomohiro ;

Onodera, Taishi ;

Adachi, Yu ;

Moriyama, Saya ;

Terahara, Kazutaka ;

Tachikawa, Natsuo ;

Yoshimura, Yoshihiro ;

Sasaki, Hiroaki ;

Horiuchi, Hiroshi ;

Miyata, Nobuyuki ;

Miyazaki, Kazuhito ;

Koga, Michiko ;

Ikeuchi, Kazuhiko ;

Nagai, Hiroyuki ;

Saito, Makoto ;

Adachi, Eisuke ;

Yotsuyanagi, Hiroshi ;

Kutsuna, Satoshi ;

Kawashima, Akira ;

Miyazato, Yusuke ;

Kinoshita, Noriko ;

Kouno, Chiyoko ;

Tanaka, Kensuke ;

Takahashi, Yoshimasa ;

Suzuki, Tadaki ;

Matano, Tetsuro ;

Ohashi, Jun ;

Kawana-Tachikawa, Ai .

HLA, 2021, 98 (01) :37-42

[7] Dynamics of anti-SARS-CoV-2 IgG antibodies post-COVID-19 in a Brazilian Amazon population [J].

Araujo Bichara, Carlos David ;

Graca Amoras, Ednelza da Silva ;

Vaz, Gergiane Lopes ;

da Silva Torres, Maria Karoliny ;

Freitas Queiroz, Maria Alice ;

Costa do Amaral, Isabella Pinheiro ;

Vieira Cayres Vallinoto, Izaura Maria ;

Carneiro Bichara, Clea Nazare ;

Rosario Vallinoto, Antonio Carlos .

BMC INFECTIOUS DISEASES, 2021, 21 (01)

[8] Presymptomatic SARS-CoV-2 Infections and Transmission in a Skilled Nursing Facility [J].

Arons, M. M. ;

Hatfield, K. M. ;

Reddy, S. C. ;

Kimball, A. ;

James, A. ;

Jacobs, J. R. ;

Taylor, J. ;

Spicer, K. ;

Bardossy, A. C. ;

Oakley, L. P. ;

Tanwar, S. ;

Dyal, J. W. ;

Harney, J. ;

Chisty, Z. ;

Bell, J. M. ;

Methner, M. ;

Paul, P. ;

Carlson, C. M. ;

McLaughlin, H. P. ;

Thornburg, N. ;

Tong, S. ;

Tamin, A. ;

Tao, Y. ;

Uehara, A. ;

Harcourt, J. ;

Clark, S. ;

Brostrom-Smith, C. ;

Page, L. C. ;

Kay, M. ;

Lewis, J. ;

Montgomery, P. ;

Stone, N. D. ;

Clark, T. A. ;

Honein, M. A. ;

Duchin, J. S. ;

Jernigan, J. A. .

NEW ENGLAND JOURNAL OF MEDICINE, 2020, 382 (22) :2081-2090

[9] ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy [J].

Asselta, Rosanna ;

Paraboschi, Elvezia Maria ;

Mantovani, Alberto ;

Duga, Stefano .

AGING-US, 2020, 12 (11) :10087-10098

[10] Evidence for Camel-to-Human Transmission of MERS Coronavirus [J].

Azhar, Esam I. ;

El-Kafrawy, Sherif A. ;

Farraj, Suha A. ;

Hassan, Ahmed M. ;

Al-Saeed, Muneera S. ;

Hashem, Anwar M. ;

Madani, Tariq A. .

NEW ENGLAND JOURNAL OF MEDICINE, 2014, 370 (26) :2499-2505

← 1 2 3 4 5 6 7 8 9 10 →