Time to treat metabolic acidosis in ICU with sodium bicarbonate? Maybe

[1] BICARBONATE DOES NOT IMPROVE HEMODYNAMICS IN CRITICALLY ILL PATIENTS WHO HAVE LACTIC-ACIDOSIS - A PROSPECTIVE, CONTROLLED CLINICAL-STUDY [J]. ANNALS OF INTERNAL MEDICINE, 1990, 112 (07) : 492 - 498

[2] Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial [J]. LANCET, 2018, 392 (10141) : 31 - 40

[3] Joannes-Boyau O, 2018, ANAESTH CRIT CARE PA

[4] Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. a prospective, multiple-center study [J]. CRITICAL CARE, 2011, 15 (05)

[5] Use of base in the treatment of acute severe organic acidosis by nephrologists and critical care physicians: Results of an online survey [J]. Clinical and Experimental Nephrology, 2006, 10 (2) : 111 - 117

[6] Zhang Z, 2018, INTENSIVE CARE MED

[1] BICARBONATE DOES NOT IMPROVE HEMODYNAMICS IN CRITICALLY ILL PATIENTS WHO HAVE LACTIC-ACIDOSIS - A PROSPECTIVE, CONTROLLED CLINICAL-STUDY [J]. ANNALS OF INTERNAL MEDICINE, 1990, 112 (07) : 492 - 498

[2] Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial [J]. LANCET, 2018, 392 (10141) : 31 - 40

[3] Joannes-Boyau O, 2018, ANAESTH CRIT CARE PA

[4] Severe metabolic or mixed acidemia on intensive care unit admission: incidence, prognosis and administration of buffer therapy. a prospective, multiple-center study [J]. CRITICAL CARE, 2011, 15 (05)

[5] Use of base in the treatment of acute severe organic acidosis by nephrologists and critical care physicians: Results of an online survey [J]. Clinical and Experimental Nephrology, 2006, 10 (2) : 111 - 117

[6] Zhang Z, 2018, INTENSIVE CARE MED